{"id":9694,"date":"2026-04-09T21:59:46","date_gmt":"2026-04-09T21:59:46","guid":{"rendered":"https:\/\/sepro.vn\/?p=9694"},"modified":"2026-04-10T08:26:02","modified_gmt":"2026-04-10T08:26:02","slug":"chon-hoa-chat-khu-khuan-theo-loai-vi-sinh-thuong-gap","status":"publish","type":"post","link":"https:\/\/sepro.vn\/vi\/chon-hoa-chat-khu-khuan-theo-loai-vi-sinh-thuong-gap\/","title":{"rendered":"C\u00e1ch Ch\u1ecdn H\u00f3a Ch\u1ea5t Kh\u1eed Khu\u1ea9n Theo Lo\u1ea1i Vi Sinh Th\u01b0\u1eddng G\u1eb7p Cho Nh\u00e0 M\u00e1y D\u01b0\u1ee3c \u2014 H\u01b0\u1edbng D\u1eabn Th\u1ef1c T\u1ebf"},"content":{"rendered":"

Trong th\u1ef1c t\u1ebf v\u1eadn h\u00e0nh ph\u00f2ng s\u1ea1ch GMP, kh\u00f4ng c\u00f3 h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n n\u00e0o c\u00f3 hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i vi sinh v\u1eadt. M\u1ed9t t\u00e1c nh\u00e2n di\u1ec7t n\u1ea5m c\u00f3 th\u1ec3 kh\u00f4ng hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi virus, trong khi alcohol ch\u1ec9 t\u00e1c \u0111\u1ed9ng l\u00ean vi khu\u1ea9n sinh d\u01b0\u1ee1ng v\u00e0 kh\u00f4ng di\u1ec7t \u0111\u01b0\u1ee3c b\u00e0o t\u1eed. Trong ng\u00e0nh d\u01b0\u1ee3c ph\u1ea9m. Vi\u1ec7c l\u1ef1a ch\u1ecdn h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n theo lo\u1ea1i vi sinh<\/a><\/strong> kh\u00f4ng ph\u00f9 h\u1ee3p c\u00f3 th\u1ec3 t\u1ea1o ra kho\u1ea3ng tr\u1ed1ng trong ki\u1ec3m so\u00e1t vi sinh, l\u00e0m t\u0103ng nguy c\u01a1 \u00f4 nhi\u1ec5m v\u00e0 \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m\u00a0<\/span><\/p>\n

SEPRO<\/strong><\/a>, v\u1edbi kinh nghi\u1ec7m h\u01a1n m\u01b0\u1eddi n\u0103m trong vi\u1ec7c ki\u1ec3m so\u00e1t vi sinh ph\u00f2ng s\u1ea1ch, ch\u00fang t\u00f4i \u0111\u00e3 m\u00e0y m\u00f2, t\u00ecm ki\u1ebfm v\u00e0 \u0111\u00fac k\u1ebft l\u1ea1i \u1edf b\u00e0i vi\u1ebft n\u00e0y.B\u1eb1ng nh\u1eefng ki\u1ebfn th\u1ee9c v\u00e0<\/span> tr\u1ea3i nghi\u1ec7m ch\u00fang t\u00f4i hy v\u1ecdng s\u1ebd gi\u00fap b\u1ea1n hi\u1ec3u r\u00f5 ph\u1ed5 t\u00e1c d\u1ee5ng c\u1ee7a t\u1eebng lo\u1ea1i h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n chuy\u00ean d\u1ee5ng cho ph\u00f2ng s\u1ea1ch, c\u00e1ch x\u00e1c \u0111\u1ecbnh lo\u1ea1i vi sinh n\u00e0o \u0111ang \u0111e d\u1ecda ph\u00f2ng s\u1ea1ch c\u1ee7a b\u1ea1n, v\u00e0 l\u00e0m th\u1ebf n\u00e0o \u0111\u1ec3 ch\u1ecdn \u0111\u00fang h\u00f3a ch\u1ea5t cho \u0111\u00fang v\u1edbi nhu c\u1ea7u c\u1ee7a nh\u00e0 m\u00e1y.<\/span><\/p>\n

T\u1ea1i Sao Kh\u00f4ng Ph\u1ea3i T\u1ea5t C\u1ea3 H\u00f3a Ch\u1ea5t \u0110\u1ec1u Gi\u1ed1ng Nhau?<\/b><\/h2>\n
\"tai-sao-khong-phai-tat-ca-hoa-chat-deu-giong-nhau\"
T\u1ea1i Sao Kh\u00f4ng Ph\u1ea3i T\u1ea5t C\u1ea3 H\u00f3a Ch\u1ea5t \u0110\u1ec1u Gi\u1ed1ng Nhau?<\/em><\/figcaption><\/figure>\n

Khi v\u1eadn h\u00e0nh th\u1ef1c t\u1ebf, m\u1ed9t quan ni\u1ec7m sai ph\u1ed5 bi\u1ebfn<\/strong> m\u00e0 c\u00e1c nh\u00e0 m\u00e1y m\u1eafc ph\u1ea3i: Lu\u00f4n ngh\u0129 r\u1eb1ng <\/strong>h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n c\u00f3 th\u1ec3 hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i vi sinh v\u1eadt<\/strong>. Tuy nhi\u00ean, m\u1ed7i nh\u00f3m vi sinh v\u1eadt (vi khu\u1ea9n, virus, n\u1ea5m, b\u00e0o t\u1eed) c\u00f3 c\u1ea5u tr\u00fac sinh h\u1ecdc v\u00e0 c\u00e1c bi\u1ebfn th\u1ec3 kh\u00e1c nhau, \u0111i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn s\u1ef1 kh\u00e1c bi\u1ec7t \u0111\u00e1ng k\u1ec3 v\u1ec1 “s\u1ee9c \u0111\u1ec1 kh\u00e1ng<\/em>” c\u1ee7a ch\u00fang v\u1edbi t\u1eebng lo\u1ea1i<\/span> h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n. <\/span><\/p>\n

C\u1ee5 th\u1ec3 h\u01a1n, alcohol c\u00f3 th\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 nhanh<\/strong> \u0111\u1ed1i v\u1edbi virus c\u00f3 v\u1ecf lipid<\/strong>, nh\u01b0ng l\u1ea1i kh\u00f4ng hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi virus kh\u00f4ng c\u00f3 v\u1ecf lipid nh\u01b0 Staphylococcus ho\u1eb7c norovirus<\/em><\/strong>. QUAT mang l\u1ea1i hi\u1ec7u qu\u1ea3 cao \u0111\u1ed1i v\u1edbi vi khu\u1ea9n Gram d\u01b0\u01a1ng (v\u00ed d\u1ee5 <\/span>Staphylococcus<\/span><\/i>), nh\u01b0ng hi\u1ec7u qu\u1ea3 l\u1ea1i k\u00e9m \u0111i khi s\u1eed d\u1ee5ng cho vi khu\u1ea9n Gram \u00e2m nh\u01b0 <\/span>Pseudomonas<\/i><\/strong>.<\/span>\u00a0N\u1ebfu b\u1ea1n mu\u1ed1n ki\u1ec3m so\u00e1t b\u00e0o t\u1eed vi khu\u1ea9n h\u00e3y th\u1eed xem qua c\u00e1c gi\u1ea3i ph\u00e1p kh\u1eed khu\u1ea9n chuy\u00ean d\u1ee5ng nh\u01b0 Acid Peracetic<\/a><\/strong> ho\u1eb7c c\u00e1c d\u1eabn xu\u1ea5t c\u1ee7a Chlorine v\u1edbi c\u00e1c \u0111\u1eb7c t\u00ednh di\u1ec7t b\u00e0o t\u1eed<\/b> (sporicidal) \u0111i\u1ec1u n\u00e0y s\u1ebd ph\u00f9 h\u1ee3p h\u01a1n cho nh\u1eefng m\u00f4i tr\u01b0\u1eddng y\u00eau c\u1ea7u s\u1ea3n xu\u1ea5t nghi\u00eam ng\u1eb7t.<\/span><\/p>\n

Do \u0111\u00f3, vi\u1ec7c l\u1ef1a ch\u1ecdn h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n kh\u00f4ng th\u1ec3 \u00e1p d\u1ee5ng m\u1ed9t gi\u1ea3i ph\u00e1p duy nh\u1ea5t cho m\u1ecdi m\u00f4i tr\u01b0\u1eddng, m\u1ecdi tr\u01b0\u1eddng h\u1ee3p, m\u00e0 c\u1ea7n ph\u1ea3i d\u1ef1a tr\u00ean vi\u1ec7c x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c v\u1ec1 nh\u1eefng \u0111\u1eb7c \u0111i\u1ec3m vi sinh, c\u00e1c ph\u1ed5 t\u00e1c d\u1ee5ng c\u1ee7a h\u00f3a ch\u1ea5t, ph\u00e2n lo\u1ea1i c\u00e1c khu v\u1ef1c (Grade) ph\u00f2ng s\u1ea1ch v\u00e0 \u0111i\u1ec1u ki\u1ec7n v\u1eadn h\u00e0nh th\u1ef1c t\u1ebf c\u1ee7a nh\u00e0 m\u00e1y \u0111\u1ec3 ch\u1ecdn \u0111\u00fang lo\u1ea1i h\u00f3a ch\u1ea5t cho lo\u1ea1i vi sinh m\u00e0 b\u1ea1n c\u1ea7n ki\u1ec3m so\u00e1t.<\/span><\/p>\n

Ph\u00e2n Bi\u1ec7t Virus C\u00f3 V\u1ecf v\u00e0 Kh\u00f4ng C\u00f3 V\u1ecf Lipid \u2014 L\u1ed7 H\u1ed5ng Ki\u1ebfn Th\u1ee9c L\u1edbn Nh\u1ea5t<\/b><\/h2>\n

M\u1ed9t s\u1ed1 nh\u1eefng sai s\u00f3t ph\u1ed5 bi\u1ebfn<\/strong> trong th\u1ef1c h\u00e0nh l\u00e0 xem t\u1ea5t c\u1ea3 virus nh\u01b0 m\u1ed9t nh\u00f3m \u0111\u1ed3ng nh\u1ea5t v\u00e0 \u00e1p d\u1ee5ng c\u00f9ng m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p kh\u1eed khu\u1ea9n. Tuy nhi\u00ean, virus \u0111\u01b0\u1ee3c chia th\u00e0nh hai nh\u00f3m ch\u00ednh v\u1edbi nh\u1eefng “s\u1ee9c \u0111\u1ec1 kh\u00e1ng<\/em>” kh\u00e1c nhau.<\/span><\/p>\n

Virus c\u00f3 v\u1ecf lipid<\/strong> s\u1ebd nh\u1ea1y c\u1ea3m v\u1edbi h\u00f3a ch\u1ea5t kh\u1eed khu\u1ea9n g\u1ed1c c\u1ed3n do l\u1edbp v\u1ecf lipid d\u1ec5 b\u1ecb ph\u00e1 v\u1ee1 b\u1edfi c\u00e1c lo\u1ea1i nh\u01b0 alcohol, QUAT. <\/span><\/p>\n

Ng\u01b0\u1ee3c l\u1ea1i, virus kh\u00f4ng c\u00f3 v\u1ecf lipid<\/strong> (v\u00ed d\u1ee5 poliovirus, Staphylococcus, parvovirus, norovirus) c\u00f3 m\u1ee9c \u0111\u1ed9 kh\u00e1ng h\u00f3a ch\u1ea5t<\/strong> cao h\u01a1n do \u0111\u01b0\u1ee3c b\u1ea3o v\u1ec7 b\u1edfi c\u1ea5u tr\u00fac capsid protein<\/strong> b\u1ec1n v\u1eefng, n\u00ean c\u1ea7n ph\u1ea3i s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i h\u00f3a ch\u1ea5t chuy\u00ean d\u1ee5ng h\u01a1n.<\/span><\/p>\n

Do \u0111\u00f3, vi\u1ec7c l\u1ef1a ch\u1ecdn ph\u01b0\u01a1ng ph\u00e1p kh\u1eed khu\u1ea9n c\u1ea7n d\u1ef1a tr\u00ean c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a t\u1eebng nh\u00f3m virus v\u00e0 \u0111i\u1ec1u ki\u1ec7n v\u1eadn h\u00e0nh th\u1ef1c t\u1ebf trong ph\u00f2ng s\u1ea1ch GMP c\u1ee7a t\u1eebng nh\u00e0 m\u00e1y.<\/span><\/p>\n

V\u00ed d\u1ee5 th\u1ef1c t\u1ebf:<\/b><\/p>\n

SARS-CoV-2:<\/b> V\u1ecf lipid m\u1ecfng s\u1ebd b\u1ecb ti\u00eau di\u1ec7t b\u1edfi <\/span>alcohol 70%<\/b><\/a> trong v\u00e0i gi\u00e2y trong 2 ph\u00fat<\/span><\/p>\n

Staphylococcus virus:<\/b> Lo\u1ea1i virus kh\u00f4ng c\u00f3 v\u1ecf th\u00ec c\u1ea7n ph\u1ea3i l\u00e0 chlorine 1000+ ppm ho\u1eb7c <\/span>PEROXY 6%<\/b> (SEPRO) v\u1edbi contact time 30 ph\u00fat<\/strong><\/span><\/p>\n

Xem th\u00eam t\u1ea1i <\/span><\/i>IPA V\u00c0 ETHANOL TRONG D\u01af\u1ee2C PH\u1ea8M \u0110\u00c2U L\u00c0 L\u1ef0A CH\u1eccN PH\u00d9 H\u1ee2P?<\/i><\/a><\/strong> \u0111\u1ec3 hi\u1ec3u c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a t\u1eebng lo\u1ea1i alcohol v\u1edbi virus c\u00f3 v\u00e0 kh\u00f4ng c\u00f3 v\u1ecf lipid.<\/span><\/i><\/p>\n

5 Lo\u1ea1i Vi Sinh Th\u01b0\u1eddng G\u1eb7p Trong Ph\u00f2ng S\u1ea1ch GMP V\u00e0 C\u00e1ch Ch\u1ecdn H\u00f3a Ch\u1ea5t Ph\u00f9 H\u1ee3p<\/b><\/h2>\n
\"5-loai-vi-sinh-thuong-gap-trong-phong-sach-gmp\"
5 Lo\u1ea1i Vi Sinh Th\u01b0\u1eddng G\u1eb7p Trong Ph\u00f2ng S\u1ea1ch GMP V\u00e0 C\u00e1ch Ch\u1ecdn H\u00f3a Ch\u1ea5t Ph\u00f9 H\u1ee3p<\/em><\/figcaption><\/figure>\n

Vi Khu\u1ea9n Gram D\u01b0\u01a1ng (Staphylococcus aureus, Bacillus):<\/b><\/h3>\n

Nh\u1ea1y c\u1ea3m v\u1edbi: <\/b>QUAT<\/b><\/a>, alcohol, H2O2<\/span><\/p>\n