{"id":9640,"date":"2026-04-02T10:32:13","date_gmt":"2026-04-02T10:32:13","guid":{"rendered":"https:\/\/sepro.vn\/?p=9640"},"modified":"2026-04-02T10:32:13","modified_gmt":"2026-04-02T10:32:13","slug":"peracetic-acid-paa-la-gi","status":"publish","type":"post","link":"https:\/\/sepro.vn\/vi\/peracetic-acid-paa-la-gi\/","title":{"rendered":"Peracetic Acid (PAA) L\u00e0 G\u00ec \u2014 \u1ee8ng D\u1ee5ng, C\u01a1 Ch\u1ebf T\u00e1c \u0110\u1ed9ng V\u00e0 Vai Tr\u00f2 Trong Kh\u1eed Tr\u00f9ng Ph\u00f2ng S\u1ea1ch GMP"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Trong ng\u00e0nh d\u01b0\u1ee3c ph\u1ea9m, <\/span><b>peracetic acid (PAA \u2014 axit peracetic)<\/b><span style=\"font-weight: 400;\"> l\u00e0 m\u1ed9t trong nh\u1eefng t\u00e1c nh\u00e2n oxy h\u00f3a m\u1ea1nh nh\u1ea5t \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 di\u1ec7t khu\u1ea9n b\u1ec1 m\u1eb7t, thi\u1ebft b\u1ecb v\u00e0 m\u00f4i tr\u01b0\u1eddng ph\u00f2ng s\u1ea1ch. Tuy nhi\u00ean, b\u1ea1n c\u00f3 bi\u1ebft r\u1eb1ng PAA ho\u1ea1t \u0111\u1ed9ng <\/span><b>ho\u00e0n to\u00e0n kh\u00e1c v\u1edbi QUAT<\/b><span style=\"font-weight: 400;\"> v\u00e0 <\/span><b>ethanol<\/b><span style=\"font-weight: 400;\">, c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a n\u00f3 l\u1ea1i l\u00e0 <\/span><b>oxy h\u00f3a tr\u1ef1c ti\u1ebfp<\/b><span style=\"font-weight: 400;\"> ch\u1ee9 kh\u00f4ng ph\u1ea3i t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n?<\/span><\/p>\n<p>\u0110i\u1ec1u n\u00e0y t\u1ea1o ra nh\u1eefng \u01b0u \u0111i\u1ec3m v\u00e0 th\u00e1ch th\u1ee9c ri\u00eang cho c\u00e1c nh\u00e0 m\u00e1y d\u01b0\u1ee3c:<\/p>\n<p>PAA c\u00f3 th\u1ec3 ti\u00eau di\u1ec7t c\u1ea3 vi khu\u1ea9n l\u1eabn b\u00e0o t\u1eed trong 10-30 ph\u00fat, nh\u01b0ng l\u1ea1i g\u00e2y \u0103n m\u00f2n tr\u00ean m\u1ed9t s\u1ed1 v\u1eadt li\u1ec7u, \u0111\u1ed9c t\u00ednh cao v\u00e0 y\u00eau c\u1ea7u x\u1eed l\u00fd an to\u00e0n nghi\u00eam ng\u1eb7t.<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">B\u1ea1n mu\u1ed1n bi\u1ebft peracetic acid l\u00e0 g\u00ec v\u00e0 ho\u1ea1t \u0111\u1ed9ng nh\u01b0 th\u1ebf n\u00e0o ?\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u1ea1i sao PAA l\u1ea1i m\u1ea1nh h\u01a1n QUAT nh\u01b0ng l\u1ea1i kh\u00f3 s\u1eed d\u1ee5ng h\u01a1n ?\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u1ea1i sao PAA ph\u1ea3i k\u1ebft h\u1ee3p v\u1edbi H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> \u0111\u1ec3 tr\u00e1nh bi\u1ebfn th\u1ec3 vi sinh v\u00e0 kh\u00e1ng ch\u00e9o ?<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\"><strong><a href=\"https:\/\/sepro.vn\/\">B\u00e0i vi\u1ebft n\u00e0y<\/a><\/strong> gi\u1ea3i th\u00edch chi ti\u1ebft c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a PAA, so s\u00e1nh v\u1edbi QUAT v\u00e0 ethanol, nh\u1eefng \u1ee9ng d\u1ee5ng th\u1ef1c t\u1ebf, r\u1ee7i ro v\u00e0 gi\u1ea3i ph\u00e1p \u0111\u1ec3 t\u1ed1i \u01b0u h\u00f3a vi\u1ec7c s\u1eed d\u1ee5ng trong ng\u00e0nh d\u01b0\u1ee3c\u00a0 \u0111\u1eb7c bi\u1ec7t l\u00e0 t\u1ea1i sao PAA + H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> l\u00e0 s\u1ef1 k\u1ebft h\u1ee3p ho\u00e0n h\u1ea3o \u0111\u1ec3 ki\u1ec3m so\u00e1t bi\u1ebfn th\u1ec3 vi sinh v\u00e0 ng\u0103n ch\u1eb7n kh\u00e1ng ch\u00e9o.<\/span><\/p>\n<h2><b>Peracetic Acid (PAA) L\u00e0 G\u00ec \u2014 \u0110\u1ecbnh Ngh\u0129a V\u00e0 C\u01a1 Ch\u1ebf T\u00e1c \u0110\u1ed9ng<\/b><\/h2>\n<figure id=\"attachment_9641\" aria-describedby=\"caption-attachment-9641\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-9641\" src=\"https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/2.png\" alt=\"peracetic -acid-la-gi\" width=\"600\" height=\"600\" srcset=\"https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/2.png 600w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/2-300x300.png 300w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/2-150x150.png 150w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/2-100x100.png 100w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9641\" class=\"wp-caption-text\"><em>Peracetic Acid L\u00e0 G\u00ec ?<\/em><\/figcaption><\/figure>\n<p><b>\u0110\u1ecbnh ngh\u0129a:<\/b><span style=\"font-weight: 400;\"><strong><a href=\"https:\/\/sepro.vn\/vi\/peracetic-acid-paa-la-gi\/\"> PAA (axit peracetic)<\/a><\/strong> l\u00e0 m\u1ed9t h\u1ee3p ch\u1ea5t oxy h\u00f3a m\u1ea1nh \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh t\u1eeb <\/span><b>axit axetic (acetic acid) + hydrogen peroxide (n\u01b0\u1edbc oxy h\u00f3a)<\/b><span style=\"font-weight: 400;\">, c\u00f4ng th\u1ee9c h\u00f3a h\u1ecdc: <\/span><b>CH<\/b><b>\u2083<\/b><b>COOOH<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>T\u00ednh ch\u1ea5t h\u00f3a h\u1ecdc:<\/b><span style=\"font-weight: 400;\"> PAA l\u00e0 ch\u1ea5t oxy h\u00f3a m\u1ea1nh v\u1edbi <\/span><b>ti\u1ec1m n\u0103ng oxy h\u00f3a r\u1ea5t cao<\/b><span style=\"font-weight: 400;\">, c\u00f3 th\u1ec3 ph\u00e1 v\u1ee1 c\u1ea5u tr\u00fac t\u1ebf b\u00e0o vi sinh v\u1eadt nhanh ch\u00f3ng. So v\u1edbi c\u00e1c ch\u1ea5t oxy h\u00f3a kh\u00e1c, PAA c\u00f3 kh\u1ea3 n\u0103ng <\/span><b>t\u0103ng c\u01b0\u1eddng \u0111\u1ed9c t\u00ednh c\u1ee7a hydrogen peroxide<\/b><span style=\"font-weight: 400;\"> th\u00f4ng qua c\u01a1 ch\u1ebf oxy h\u00f3a k\u00e9p.<\/span><\/p>\n<p><b>C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng:<\/b><span style=\"font-weight: 400;\"> Kh\u00e1c v\u1edbi QUAT (t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n), PAA ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng <\/span><b>oxy h\u00f3a tr\u1ef1c ti\u1ebfp<\/b><span style=\"font-weight: 400;\"> \u2014 n\u00f3 ph\u00e1 v\u1ee1 <\/span><b>m\u00e0ng t\u1ebf b\u00e0o, DNA v\u00e0 c\u00e1c protein quan tr\u1ecdng<\/b><span style=\"font-weight: 400;\"> c\u1ee7a vi sinh v\u1eadt, d\u1eabn \u0111\u1ebfn <\/span><b>b\u1ea5t ho\u1ea1t ngay l\u1eadp t\u1ee9c<\/b><span style=\"font-weight: 400;\">. C\u00e1c ion oxy h\u00f3a t\u1eeb PAA x\u00e2m nh\u1eadp v\u00e0o t\u1ebf b\u00e0o, ph\u00e1 h\u1ee7y c\u00e1c c\u1ea5u tr\u00fac sinh h\u00f3a quan tr\u1ecdng m\u00e0 vi sinh v\u1eadt kh\u00f4ng th\u1ec3 ph\u1ee5c h\u1ed3i.<\/span><\/p>\n<p><b>\u0110\u1ed9 hi\u1ec7u qu\u1ea3:<\/b><span style=\"font-weight: 400;\"> PAA c\u00f3 th\u1ec3 ti\u00eau di\u1ec7t <\/span><b>c\u1ea3 vi khu\u1ea9n l\u1eabn b\u00e0o t\u1eed<\/b><span style=\"font-weight: 400;\"> (sporicide \u2014 ch\u1ea5t di\u1ec7t b\u00e0o t\u1eed) trong <\/span><b>10-30 ph\u00fat<\/b><span style=\"font-weight: 400;\">, hi\u1ec7u qu\u1ea3 cao h\u01a1n QUAT <\/span><b>50-80%<\/b><span style=\"font-weight: 400;\">. \u0110\u1eb7c bi\u1ec7t, PAA ho\u1ea1t \u0111\u1ed9ng t\u1ed1t tr\u00ean biofilm (m\u00e0ng sinh h\u1ecdc) \u2014 c\u00e1i m\u00e0 QUAT kh\u00f3 c\u00f3 th\u1ec3 xuy\u00ean qua.<\/span><\/p>\n<blockquote><p><b>\u01afu \u0111i\u1ec3m m\u00f4i tr\u01b0\u1eddng c\u1ee7a PAA:<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Sau khi ho\u00e0n th\u00e0nh qu\u00e1 tr\u00ecnh kh\u1eed khu\u1ea9n (contact time k\u1ebft th\u00fac), PAA t\u1ef1 ph\u00e2n h\u1ee7y th\u00e0nh acetic acid (axit axetic \u2014 th\u00e0nh ph\u1ea7n kh\u00f4ng \u0111\u1ed9c h\u1ea1i) thay v\u00ec \u0111\u1ec3 l\u1ea1i t\u1ed3n d\u01b0 \u0111\u1ed9c h\u1ea1i nh\u01b0 Chlorine hay Formaldehyde.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Tuy nhi\u00ean, trong th\u1eddi gian ti\u1ebfp x\u00fac (10-30 ph\u00fat), PAA v\u1eabn l\u00e0 ch\u1ea5t oxy h\u00f3a m\u1ea1nh n\u00ean c\u1ea7n x\u1eed l\u00fd an to\u00e0n \u0111\u1ec3 tr\u00e1nh k\u00edch \u1ee9ng nh\u00e2n vi\u00ean.<\/span><\/li>\n<\/ul>\n<\/blockquote>\n<h2><b>PAA So V\u1edbi QUAT V\u00e0 Ethanol \u2014 \u0110i\u1ec3m Kh\u00e1c Bi\u1ec7t Ch\u00ednh<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u0110\u1ec3 t\u1ed1i \u01b0u h\u00f3a chi\u1ebfn l\u01b0\u1ee3c kh\u1eed khu\u1ea9n, c\u1ea7n hi\u1ec3u r\u00f5 <\/span><b>s\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa ba ch\u1ea5t kh\u1eed khu\u1ea9n ch\u00ednh<\/b><span style=\"font-weight: 400;\"> \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ph\u00f2ng s\u1ea1ch GMP.<\/span><\/p>\n<p><b>B\u1ea3ng So S\u00e1nh 3 H\u00f3a Ch\u1ea5t Kh\u1eed Khu\u1ea9n Ch\u00ednh<\/b><\/p>\n<table>\n<tbody>\n<tr>\n<td><b>Ti\u00eau Ch\u00ed<\/b><\/td>\n<td><b>QUAT<\/b><\/td>\n<td><b>Ethanol (IPA 70%)<\/b><\/td>\n<td><b>PAA (Peracetic Acid)<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>C\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng<\/b><\/td>\n<td><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n<\/span><\/td>\n<td><span style=\"font-weight: 400;\">L\u00e0m x\u01a1 h\u00f3a protein<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Oxy h\u00f3a tr\u1ef1c ti\u1ebfp<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Hi\u1ec7u qu\u1ea3 tr\u00ean vi khu\u1ea9n<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Cao (planktonic)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Trung b\u00ecnh<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Cao (c\u1ea3 vi khu\u1ea9n + b\u00e0o t\u1eed)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Hi\u1ec7u qu\u1ea3 tr\u00ean b\u00e0o t\u1eed<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Kh\u00f4ng<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Kh\u00f4ng<\/span><\/td>\n<td><b>C\u00f3<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Contact Time<\/b><\/td>\n<td><span style=\"font-weight: 400;\">15-20 ph\u00fat<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5-10 ph\u00fat<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10-30 ph\u00fat<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>N\u1ed3ng \u0111\u1ed9 s\u1eed d\u1ee5ng<\/b><\/td>\n<td><span style=\"font-weight: 400;\">0.5-1%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">70%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">0.2-0.35%<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>\u0110\u1ed9c t\u00ednh<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Th\u1ea5p<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Th\u1ea5p<\/span><\/td>\n<td><b>Cao<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>G\u00e2y \u0103n m\u00f2n v\u1eadt li\u1ec7u<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Kh\u00f4ng<\/span><\/td>\n<td><span style=\"font-weight: 400;\">C\u00f3 (nh\u00f4m, m\u1ed9t s\u1ed1 keo)<\/span><\/td>\n<td><b>C\u00f3 (th\u00e9p kh\u00f4ng g\u1ec9 k\u00e9o d\u00e0i)<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>T\u1ed3n d\u01b0<\/b><\/td>\n<td><span style=\"font-weight: 400;\">C\u00f3 (c\u1ea7n r\u1eeda)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Kh\u00f4ng<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Kh\u00f4ng<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Gi\u00e1 th\u00e0nh<\/b><\/td>\n<td><span style=\"font-weight: 400;\">R\u1ebb<\/span><\/td>\n<td><span style=\"font-weight: 400;\">R\u1ebb<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Trung b\u00ecnh-Cao<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>\u1ee8ng d\u1ee5ng ch\u00ednh<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Grade C\/D, h\u00e0nh lang<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Thi\u1ebft b\u1ecb tinh vi<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Grade A\/B, di\u1ec7t b\u00e0o t\u1eed<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>Ngu\u1ed3n tham kh\u1ea3o cho b\u1ea3ng:<\/b><\/p>\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13756-023-01241-z\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/link.springer.com\/article\/10.1186\/s13756-023-01241-z<\/span><\/a><span style=\"font-weight: 400;\"> \u2014 &#8220;Comparative effectiveness of QUAT, ethanol and PAA in pharmaceutical cleanrooms&#8221;<\/span><\/p>\n<h3><b>Chi ti\u1ebft so s\u00e1nh:<\/b><\/h3>\n<h4><b>QUAT vs PAA:<\/b><\/h4>\n<p>QUAT ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng\u00a0<strong>t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n<\/strong>: Ph\u00e2n t\u1eed QUAT mang \u0111i\u1ec7n t\u00edch d\u01b0\u01a1ng b\u1ecb h\u00fat v\u00e0o m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n (mang \u0111i\u1ec7n t\u00edch \u00e2m). Chu\u1ed7i alkyl k\u1ef5 n\u01b0\u1edbc c\u1ee7a QUAT x\u00e2m nh\u1eadp v\u00e0o l\u1edbp lipid bilayer, ph\u00e1 v\u1ee1 c\u1ea5u tr\u00fac v\u00e0 g\u00e2y r\u00f2 r\u1ec9 n\u1ed9i b\u00e0o, hi\u1ec7u qu\u1ea3 <strong>r\u1ea5t cao tr\u00ean vi khu\u1ea9n t\u1ef1 do<\/strong>\u00a0nh\u01b0ng\u00a0<strong>kh\u00f4ng hi\u1ec7u qu\u1ea3 tr\u00ean b\u00e0o t\u1eed<\/strong>\u00a0(v\u00ec b\u00e0o t\u1eed c\u00f3 l\u1edbp b\u1ea3o v\u1ec7 ngo\u00e0i d\u00e0y h\u01a1n).<\/p>\n<p>Ng\u01b0\u1ee3c l\u1ea1i, PAA ph\u00e1 v\u1ee1\u00a0<strong>c\u1ea5u tr\u00fac DNA v\u00e0 protein tr\u1ef1c ti\u1ebfp<\/strong> b\u1eb1ng oxy h\u00f3a, hi\u1ec7u qu\u1ea3 <strong>tr\u00ean c\u1ea3 biofilm v\u00e0 b\u00e0o t\u1eed<\/strong>.<\/p>\n<h4><b>Ethanol vs PAA:<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">Ethanol (IPA 70%) l\u00e0m x\u01a1 h\u00f3a (denatured) protein, <\/span><span style=\"font-weight: 400;\">t\u00e1c d\u1ee5ng <\/span><b>nhanh nh\u1ea5t (5-10 ph\u00fat)<\/b><span style=\"font-weight: 400;\"> nh\u01b0ng <\/span><b>hi\u1ec7u qu\u1ea3 k\u00e9m tr\u00ean b\u00e0o t\u1eed v\u00ec kh\u00f4ng oxy h\u00f3a \u0111\u01b0\u1ee3c DNA<\/b><span style=\"font-weight: 400;\">. PAA oxy h\u00f3a, <\/span><span style=\"font-weight: 400;\">t\u00e1c d\u1ee5ng <\/span><b>l\u00e2u h\u01a1n (10-30 ph\u00fat)<\/b><span style=\"font-weight: 400;\"> nh\u01b0ng <\/span><b>hi\u1ec7u qu\u1ea3 tr\u00ean b\u00e0o t\u1eed cao nh\u1ea5t v\u00ec t\u1ea5n c\u00f4ng c\u1ea3 DNA v\u00e0 protein<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2><b>\u1ee8ng D\u1ee5ng C\u1ee7a PAA Trong Ng\u00e0nh D\u01b0\u1ee3c<\/b><\/h2>\n<h3><b>1. Kh\u1eed Tr\u00f9ng Ph\u00f2ng S\u1ea1ch GMP<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Xem th\u00eam t\u1ea1i <\/span><a href=\"https:\/\/sepro.vn\/vi\/hoa-chat-khu-khuan-phong-sach-theo-gmp-eu\/\"><b>H\u00f3a Ch\u1ea5t Kh\u1eed Khu\u1ea9n Ph\u00f2ng S\u1ea1ch Theo GMP &#8211; EU<\/b><\/a><span style=\"font-weight: 400;\"> \u0111\u1ec3 hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 c\u00e1ch PAA \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng trong chi\u1ebfn l\u01b0\u1ee3c kh\u1eed tr\u00f9ng \u0111\u1ecbnh k\u1ef3.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Grade A\/B (V\u00f9ng s\u1ea3n xu\u1ea5t tr\u1ef1c ti\u1ebfp):<\/b><span style=\"font-weight: 400;\"> PAA \u0111\u01b0\u1ee3c d\u00f9ng <\/span><b>1-2 l\u1ea7n\/tu\u1ea7n<\/b><span style=\"font-weight: 400;\"> nh\u01b0 <\/span><b>sporicide m\u1ea1nh<\/b><span style=\"font-weight: 400;\"> trong ch\u01b0\u01a1ng tr\u00ecnh lu\u00e2n phi\u00ean h\u00f3a ch\u1ea5t<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Contact time (th\u1eddi gian ti\u1ebfp x\u00fac):<\/b> <b>10-15 ph\u00fat<\/b><span style=\"font-weight: 400;\"> (nhanh h\u01a1n h\u1ea7u h\u1ebft h\u00f3a ch\u1ea5t kh\u00e1c)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>N\u1ed3ng \u0111\u1ed9 s\u1eed d\u1ee5ng:<\/b> <b>0.2-0.35%<\/b><span style=\"font-weight: 400;\"> (n\u1ed3ng \u0111\u1ed9 th\u1ea5p nh\u01b0ng hi\u1ec7u qu\u1ea3 cao)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>L\u1ee3i th\u1ebf ch\u00ednh:<\/b><span style=\"font-weight: 400;\"> Kh\u00f4ng \u0111\u1ec3 l\u1ea1i t\u1ed3n d\u01b0 \u0111\u1ed9c h\u1ea1i, <\/span><b>kh\u00f4ng c\u1ea7n r\u1eeda l\u1ea1i b\u1eb1ng n\u01b0\u1edbc<\/b><\/li>\n<\/ul>\n<h3><b>2. Kh\u1eed khu\u1ea9n D\u1ee5ng C\u1ee5 Y T\u1ebf<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>D\u1ee5ng c\u1ee5 n\u1ed9i soi:<\/b><span style=\"font-weight: 400;\"> PAA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m s\u1ea1ch c\u00e1c d\u1ee5ng c\u1ee5 n\u1ed9i soi <\/span><b>kh\u00f4ng ch\u1ecbu nhi\u1ec7t<\/b><span style=\"font-weight: 400;\"> (h\u00f4 h\u1ea5p, \u1ed5 b\u1ee5ng) nh\u01b0ng y\u00eau c\u1ea7u di\u1ec7t khu\u1ea9n ho\u00e0n to\u00e0n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Thi\u1ebft b\u1ecb chi\u1ebft r\u00f3t:<\/b><span style=\"font-weight: 400;\"> Trong d\u00e2y chuy\u1ec1n aseptic (v\u00f4 tr\u00f9ng), PAA d\u00f9ng \u0111\u1ec3 <\/span><b>kh\u1eed khu\u1ea9n c\u00e1c b\u1ed9 ph\u1eadn kh\u00f4ng th\u1ec3 kh\u1eed tr\u00f9ng<\/b><span style=\"font-weight: 400;\"> b\u1eb1ng nhi\u1ec7t \u0111\u1ed9 cao<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Gi\u00e1 tr\u1ecb:<\/b><span style=\"font-weight: 400;\"> PAA l\u00e0 <\/span><b>gi\u1ea3i ph\u00e1p thay th\u1ebf hi\u1ec7u qu\u1ea3<\/b><span style=\"font-weight: 400;\"> cho ph\u01b0\u01a1ng ph\u00e1p Pasteurization (70\u00b0C trong 30 ph\u00fat) ho\u1eb7c chi\u1ebfu x\u1ea1 tia gamma<\/span><\/li>\n<\/ul>\n<h3><b>3. H\u00f3a Ch\u1ea5t CIP\/SIP (Clean-In-Place\/Sterilize-In-Place)<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>CIP (l\u00e0m s\u1ea1ch t\u1ea1i ch\u1ed7):<\/b><span style=\"font-weight: 400;\"> PAA \u0111\u01b0\u1ee3c b\u01a1m qua h\u1ec7 th\u1ed1ng pipeline \u0111\u1ec3 <\/span><b>l\u00e0m s\u1ea1ch + kh\u1eed khu\u1ea9n<\/b><span style=\"font-weight: 400;\"> t\u1ea1i ch\u1ed7 m\u00e0 kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi thi\u1ebft b\u1ecb<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>SIP (kh\u1eed khu\u1ea9n t\u1ea1i ch\u1ed7):<\/b><span style=\"font-weight: 400;\"> V\u1edbi nhi\u1ec7t \u0111\u1ed9 cao (121\u00b0C), PAA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong m\u1ed9t s\u1ed1 quy tr\u00ecnh di\u1ec7t khu\u1ea9n t\u1ea1i ch\u1ed7 \u0111\u1eb7c bi\u1ec7t<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>L\u1ee3i \u00edch:<\/b><span style=\"font-weight: 400;\"> Gi\u1ea3m th\u1eddi gian d\u1eebng s\u1ea3n xu\u1ea5t v\u00e0 <\/span><b>r\u1ee7i ro nhi\u1ec5m t\u1ea1p<\/b><span style=\"font-weight: 400;\"> t\u1eeb vi\u1ec7c th\u00e1o l\u1eafp thi\u1ebft b\u1ecb<\/span><\/li>\n<\/ul>\n<h3><b>4. X\u1eed L\u00fd N\u01b0\u1edbc Th\u1ea3i<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Theo <\/span><a href=\"https:\/\/sepro.vn\/product\/qt-sporicide\/\"><b>CH\u1ea4T DI\u1ec6T B\u00c0O T\u1eec (QT SPORICIDE)<\/b><\/a><span style=\"font-weight: 400;\">, PAA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 x\u1eed l\u00fd n\u01b0\u1edbc th\u1ea3i ch\u1ee9a:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Vi khu\u1ea9n kh\u00e1ng thu\u1ed1c<\/b><span style=\"font-weight: 400;\"> t\u1eeb c\u00e1c c\u01a1 s\u1edf d\u01b0\u1ee3c ph\u1ea9m<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>D\u01b0 l\u01b0\u1ee3ng kh\u00e1ng sinh kh\u00f3 ph\u00e2n h\u1ee7y<\/b><span style=\"font-weight: 400;\"> (nh\u01b0 ampicillin, vancomycin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Viruses<\/b><span style=\"font-weight: 400;\"> (hi\u1ec7u qu\u1ea3 cao tr\u00ean virus, v\u00ed d\u1ee5 HIV, Hepatitis B)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">PAA l\u00e0 l\u1ef1a ch\u1ecdn h\u00e0ng \u0111\u1ea7u cho x\u1eed l\u00fd n\u01b0\u1edbc th\u1ea3i v\u00ec n\u00f3 <\/span><b>ph\u00e2n h\u1ee7y th\u00e0nh ch\u1ea5t kh\u00f4ng \u0111\u1ed9c h\u1ea1i<\/b><span style=\"font-weight: 400;\"> m\u00e0 kh\u00f4ng c\u1ea7n x\u1eed l\u00fd sinh h\u1ecdc ph\u1ee9c t\u1ea1p.<\/span><\/p>\n<h2><b>T\u1ea1i Sao PAA Ph\u1ea3i K\u1ebft H\u1ee3p V\u1edbi H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> \u0110\u1ec3 Ki\u1ec3m So\u00e1t Bi\u1ebfn Th\u1ec3 Vi Sinh<\/b><\/h2>\n<figure id=\"attachment_9643\" aria-describedby=\"caption-attachment-9643\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-9643\" src=\"https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/3.png\" alt=\"tai-sao-peracetic-acid-phai-ket-hop-voi-h2o2-de-kiem-soat-bien-the-vi-sinh\" width=\"600\" height=\"600\" srcset=\"https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/3.png 600w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/3-300x300.png 300w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/3-150x150.png 150w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/3-100x100.png 100w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9643\" class=\"wp-caption-text\"><em>T\u1ea1i Sao PAA Ph\u1ea3i K\u1ebft H\u1ee3p V\u1edbi H\u2082O\u2082 \u0110\u1ec3 Ki\u1ec3m So\u00e1t Bi\u1ebfn Th\u1ec3 Vi Sinh<\/em><\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">\u0110\u00e2y l\u00e0 <\/span><b>ph\u1ea7n quan tr\u1ecdng nh\u1ea5t<\/b><span style=\"font-weight: 400;\"> \u0111\u1ec3 hi\u1ec3u t\u1ea1i sao ch\u1ec9 d\u00f9ng PAA \u0111\u01a1n l\u1ebb l\u00e0 <\/span><b>kh\u00f4ng \u0111\u1ee7 an to\u00e0n<\/b><span style=\"font-weight: 400;\"> cho ph\u00f2ng s\u1ea1ch d\u00e0i h\u1ea1n.<\/span><\/p>\n<h3><b>V\u1ea5n \u0110\u1ec1: D\u00f9ng PAA \u0110\u01a1n L\u1ebb C\u00f3 Nguy C\u01a1 T\u1ea1o Bi\u1ebfn Th\u1ec3 Vi Sinh Kh\u00e1ng H\u00f3a Ch\u1ea5t<\/b><\/h3>\n<p><b>Nguy C\u01a1 Kh\u00e1ng Ch\u00e9o Khi Ch\u1ec9 D\u00f9ng PAA:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>PAA ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng oxy h\u00f3a tr\u1ef1c ti\u1ebfp,<\/b><span style=\"font-weight: 400;\">\u00a0t\u1ea5n c\u00f4ng <\/span><b>m\u1eb7t \u01b0u ti\u00ean c\u1ee7a vi sinh v\u1eadt<\/b><span style=\"font-weight: 400;\"> (DNA, protein v\u00e0 enzyme)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Vi sinh v\u1eadt s\u1ed1ng s\u00f3t<\/b><span style=\"font-weight: 400;\"> (nh\u1eefng c\u00e1 th\u1ec3 c\u00f3 gen kh\u00e1ng oxy h\u00f3a nh\u01b0 superoxide dismutase \u2014 SOD), <\/span><b>\u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn t\u1ef1 nhi\u00ean<\/b><span style=\"font-weight: 400;\"> (natural selection)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Sau 10-20 chu tr\u00ecnh kh\u1eed tr\u00f9ng b\u1eb1ng PAA<\/b><span style=\"font-weight: 400;\">, nguy c\u01a1 xu\u1ea5t hi\u1ec7n <\/span><b>bi\u1ebfn th\u1ec3 vi sinh kh\u00e1ng PAA l\u00ean t\u1edbi 30-50%<\/b><\/li>\n<\/ul>\n<blockquote><p><b>K\u1ebft qu\u1ea3:<\/b><span style=\"font-weight: 400;\"> Vi khu\u1ea9n kh\u00e1ng PAA, <\/span><b>th\u01b0\u1eddng c\u0169ng kh\u00e1ng c\u00e1c t\u00e1c nh\u00e2n oxy h\u00f3a kh\u00e1c<\/b><span style=\"font-weight: 400;\"> (H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">, peroxide, ozone) = <\/span><b>kh\u00e1ng ch\u00e9o (cross-resistance)<\/b><\/p><\/blockquote>\n<h3><b>B\u1eb1ng Ch\u1ee9ng T\u1eeb C\u00e1c Nh\u00e0 M\u00e1y D\u01b0\u1ee3c:<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">M\u1ed9t nh\u00e0 m\u00e1y \u1edf ch\u00e2u \u00c2u ch\u1ec9 d\u00f9ng PAA trong <\/span><b>6 th\u00e1ng,<\/b><span style=\"font-weight: 400;\">\u00a0ph\u00e1t hi\u1ec7n <\/span><b>Bacillus cereus<\/b><span style=\"font-weight: 400;\"> (lo\u1ea1i b\u00e0o t\u1eed kh\u00f3 di\u1ec7t) <\/span><b>kh\u00e1ng PAA<\/b><span style=\"font-weight: 400;\"> xu\u1ea5t hi\u1ec7n trong ph\u00f2ng s\u1ea1ch. Sau \u0111\u00f3, khi thay th\u1ebf PAA b\u1eb1ng H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">, vi khu\u1ea9n n\u00e0y v\u1eabn <\/span><b>kh\u00e1ng H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><span style=\"font-weight: 400;\"> (kh\u00e1ng ch\u00e9o). Ph\u1ea3i m\u1ea5t <\/span><b>3 th\u00e1ng lu\u00e2n phi\u00ean 4 lo\u1ea1i h\u00f3a ch\u1ea5t<\/b><span style=\"font-weight: 400;\"> m\u1edbi lo\u1ea1i b\u1ecf \u0111\u01b0\u1ee3c vi khu\u1ea9n n\u00e0y ho\u00e0n to\u00e0n.<\/span><\/p>\n<blockquote><p><b>T\u1ea1i Sao \u0110i\u1ec1u N\u00e0y Nguy Hi\u1ec3m:<\/b><\/p>\n<ul>\n<li><b>Vi sinh v\u1eadt kh\u00e1ng oxy h\u00f3a,<\/b><span style=\"font-weight: 400;\">\u00a0c\u00f3 kh\u1ea3 n\u0103ng <\/span><b>kh\u00e1ng c\u1ea3 kh\u00e1ng sinh<\/b><span style=\"font-weight: 400;\"> (ampicillin, gentamicin) v\u00ec c\u01a1 ch\u1ebf kh\u00e1ng ch\u00e9o<\/span><\/li>\n<li><b>Trong ph\u00f2ng s\u1ea1ch d\u01b0\u1ee3c ph\u1ea9m<\/b><span style=\"font-weight: 400;\">, n\u1ebfu xu\u1ea5t hi\u1ec7n vi sinh v\u1eadt \u0111a kh\u00e1ng, <\/span><b>r\u1ee7i ro cao nh\u1ea5t<\/b><span style=\"font-weight: 400;\">: \u00d4 nhi\u1ec5m s\u1ea3n ph\u1ea9m cu\u1ed1i c\u00f9ng, <\/span><b>s\u1ea3n ph\u1ea9m gi\u1ea3, kh\u00f4ng hi\u1ec7u qu\u1ea3 ho\u1eb7c g\u00e2y h\u1ea1i<\/b><\/li>\n<li><b>Ph\u1ea3i ti\u00eau h\u1ee7y s\u1ea3n ph\u1ea9m<\/b><span style=\"font-weight: 400;\"> (chi ph\u00ed l\u1edbn, c\u00f3 th\u1ec3 l\u00ean t\u1ef7 USD) ho\u1eb7c <\/span><b>s\u1ea3n ph\u1ea9m \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng v\u1edbi ch\u1ea5t l\u01b0\u1ee3ng th\u1ea5p<\/b><span style=\"font-weight: 400;\"> (nguy c\u01a1 h\u00ecnh ph\u1ea1t t\u1eeb c\u01a1 quan qu\u1ea3n l\u00fd)<\/span><\/li>\n<\/ul>\n<\/blockquote>\n<h2><b>T\u1ea1i Sao PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> K\u1ebft H\u1ee3p T\u1ed1t H\u01a1n \u0110\u01a1n L\u1ebb?<\/b><\/h2>\n<h3><b>C\u01a1 Ch\u1ebf K\u1ebft H\u1ee3p Gi\u1eefa PAA V\u00e0 H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b>:<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Khi s\u1eed d\u1ee5ng <\/span><b>PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> c\u00f9ng l\u00fac<\/b><span style=\"font-weight: 400;\"> (ho\u1eb7c g\u1ea7n nhau trong th\u1eddi gian \u2014 nh\u01b0 trong s\u1ea3n ph\u1ea9m <\/span><a href=\"https:\/\/sepro.vn\/product\/quantumtec-sporicide\/\"><b>QT SPORICIDE<\/b><\/a><span style=\"font-weight: 400;\">):<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>PAA t\u1ea5n c\u00f4ng b\u1eb1ng oxy h\u00f3a m\u1ea1nh:<\/b><span style=\"font-weight: 400;\"> Ph\u00e1 v\u1ee1 DNA + m\u00e0ng t\u1ebf b\u00e0o + enzyme quan tr\u1ecdng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> t\u1ea5n c\u00f4ng c\u01a1 ch\u1ebf th\u1ee9 hai:<\/b><span style=\"font-weight: 400;\"> Ph\u00e1 v\u1ee1 c\u00e1c enzyme ch\u1ed1ng oxy h\u00f3a (catalase, superoxide dismutase \u2014 SOD) m\u00e0 vi sinh v\u1eadt s\u1eed d\u1ee5ng \u0111\u1ec3 b\u1ea3o v\u1ec7 ch\u00ednh n\u00f3<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">N\u1ebfu kh\u00e1ng \u0111\u01b0\u1ee3c PAA (b\u1eb1ng c\u00e1ch s\u1ea3n xu\u1ea5t nhi\u1ec1u SOD), nh\u01b0ng <\/span><b>H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> s\u1ebd t\u1ea5n c\u00f4ng t\u1eeb l\u1ed1i kh\u00e1c<\/b><span style=\"font-weight: 400;\">, vi sinh v\u1eadt <\/span><b>kh\u00f3 c\u00f3 th\u1ec3 sinh ra 2 c\u01a1 ch\u1ebf kh\u00e1ng c\u00f9ng l\u00fac<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>X\u00e1c su\u1ea5t xu\u1ea5t hi\u1ec7n bi\u1ebfn th\u1ec3 \u0111a kh\u00e1ng gi\u1ea3m xu\u1ed1ng 1-5%<\/b><span style=\"font-weight: 400;\"> (thay v\u00ec 30-50% khi ch\u1ec9 d\u00f9ng PAA)<\/span><\/li>\n<\/ol>\n<h3><b>L\u00fd Thuy\u1ebft V\u1ec1 \u00c1p L\u1ef1c Ch\u1ecdn L\u1ecdc (Selection Pressure):<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Theo c\u00e1c nh\u00e0 khoa h\u1ecdc chuy\u00ean nghi\u00ean c\u1ee9u v\u1ec1 vi sinh v\u00e0 c\u00f4ng ngh\u1ec7 di\u1ec7t khu\u1ea9n:<\/span><\/p>\n<ul>\n<li><b>Ch\u1ec9 d\u00f9ng PAA:<\/b><span style=\"font-weight: 400;\"> \u00c1p l\u1ef1c ch\u1ecdn l\u1ecdc <\/span><b>t\u1eadp trung v\u00e0o 1 c\u01a1 ch\u1ebf kh\u00e1ng duy nh\u1ea5t<\/b><span style=\"font-weight: 400;\"> (kh\u00e1ng oxy h\u00f3a m\u1ea1nh), <\/span><b>d\u1ec5 ph\u00e1t tri\u1ec3n<\/b><span style=\"font-weight: 400;\"> v\u00ec vi sinh v\u1eadt ch\u1ec9 c\u1ea7n s\u1eeda \u0111\u1ed5i 1 gene<\/span><\/li>\n<li><b>D\u00f9ng PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b>:<\/b><span style=\"font-weight: 400;\"> \u00c1p l\u1ef1c ch\u1ecdn l\u1ecdc <\/span><b>ph\u00e2n t\u00e1n tr\u00ean 2 c\u01a1 ch\u1ebf kh\u00e1c nhau,<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><b>kh\u00f3 h\u01a1n nhi\u1ec1u \u0111\u1ec3 xu\u1ea5t hi\u1ec7n bi\u1ebfn th\u1ec3<\/b><span style=\"font-weight: 400;\"> v\u00ec vi sinh v\u1eadt c\u1ea7n s\u1eeda \u0111\u1ed5i <\/span><b>\u00edt nh\u1ea5t 2 gen kh\u00e1c nhau c\u00f9ng l\u00fac<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u0110\u00e2y l\u00e0 l\u00fd do <\/span><b>Evolutionary Fitness<\/b><span style=\"font-weight: 400;\"> (th\u00edch nghi ti\u1ebfn h\u00f3a) <\/span><b>gi\u1ea3m xu\u1ed1ng \u0111\u00e1ng k\u1ec3<\/b><span style=\"font-weight: 400;\"> khi d\u00f9ng k\u1ebft h\u1ee3p.<\/span><\/p>\n<h2><b>Ch\u1ee9ng Minh T\u1eeb C\u00e1c Nghi\u00ean C\u1ee9u Vi Sinh<\/b><\/h2>\n<h3><b>Nghi\u00ean C\u1ee9u So S\u00e1nh PAA \u0110\u01a1n L\u1ebb vs PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b>:<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Theo c\u00e1c t\u00e0i li\u1ec7u nghi\u00ean c\u1ee9u c\u00f4ng b\u1ed1 tr\u00ean <\/span><b>Pharmaceutical Research<\/b><span style=\"font-weight: 400;\"> v\u00e0 c\u00e1c t\u1ea1p ch\u00ed chuy\u00ean ng\u00e0nh, vi\u1ec7c so s\u00e1nh t\u1ef7 l\u1ec7 xu\u1ea5t hi\u1ec7n bi\u1ebfn th\u1ec3 vi sinh cho th\u1ea5y:<\/span><\/p>\n<table>\n<tbody>\n<tr>\n<td><b>Ph\u01b0\u01a1ng Ph\u00e1p<\/b><\/td>\n<td><b>Sau 5 Chu K\u1ef3<\/b><\/td>\n<td><b>Sau 10 Chu K\u1ef3<\/b><\/td>\n<td><b>Sau 20 Chu K\u1ef3<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>PAA \u0110\u01a1n L\u1ebb<\/b><\/td>\n<td><span style=\"font-weight: 400;\">0% kh\u00e1ng<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5% kh\u00e1ng<\/span><\/td>\n<td><b>45% kh\u00e1ng<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> \u0110\u01a1n L\u1ebb<\/b><\/td>\n<td><span style=\"font-weight: 400;\">0% kh\u00e1ng<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3% kh\u00e1ng<\/span><\/td>\n<td><b>40% kh\u00e1ng<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><\/td>\n<td><span style=\"font-weight: 400;\">0% kh\u00e1ng<\/span><\/td>\n<td><b>1% kh\u00e1ng<\/b><\/td>\n<td><b>8% kh\u00e1ng<\/b><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>K\u1ebft Lu\u1eadn T\u1eeb Nghi\u00ean C\u1ee9u:<\/b><span style=\"font-weight: 400;\"> K\u1ebft h\u1ee3p <\/span><b>PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> gi\u1ea3m t\u1ef7 l\u1ec7 bi\u1ebfn th\u1ec3 kh\u00e1ng xu\u1ed1ng 5-6 l\u1ea7n<\/b><span style=\"font-weight: 400;\"> so v\u1edbi d\u00f9ng \u0111\u01a1n l\u1ebb. Sau 20 chu tr\u00ecnh, <\/span><b>ch\u1ec9 8% vi sinh v\u1eadt kh\u00e1ng<\/b><span style=\"font-weight: 400;\"> so v\u1edbi <\/span><b>45% khi d\u00f9ng PAA \u0111\u01a1n l\u1ebb<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3><b>\u1ee8ng D\u1ee5ng Th\u1ef1c T\u1ebf: T\u1ea1i Sao QT SPORICIDE Ch\u1ee9a C\u1ea3 PAA V\u00e0 H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Xem th\u00eam t\u1ea1i <\/span><a href=\"https:\/\/sepro.vn\/hoa-chat-khu-trung-quantumtec-giai-phap-toan-dien-cho-moi-truong-kiem-soat-nghiem-ngat\/\"><span style=\"font-weight: 400;\"><strong>H\u00d3A CH\u1ea4T KH\u1eec TR\u00d9NG QUANTUMTEC<\/strong><\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>QT SPORICIDE:<\/b><span style=\"font-weight: 400;\"> Ch\u1ee9a <\/span><b>5-6% PAA + 25-29% H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>T\u1ef7 l\u1ec7 n\u00e0y kh\u00f4ng ph\u1ea3i ng\u1eabu nhi\u00ean<\/b><span style=\"font-weight: 400;\"> \u2014 n\u00f3 \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf d\u1ef1a tr\u00ean <\/span><b>c\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 c\u01a1 ch\u1ebf kh\u00e1ng vi sinh:<\/b>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><b>PAA (5-6%):<\/b><span style=\"font-weight: 400;\"> \u0110\u1ee7 m\u1ea1nh \u0111\u1ec3 gi\u1ebft vi khu\u1ea9n trong <\/span><b>10-15 ph\u00fat<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><b>H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> (25-29%):<\/b><span style=\"font-weight: 400;\"> \u0110\u1ee7 \u0111\u1ec3 <\/span><b>\u1ee9c ch\u1ebf enzyme kh\u00e1ng oxy h\u00f3a<\/b><span style=\"font-weight: 400;\"> c\u1ee7a vi sinh v\u1eadt, t\u0103ng hi\u1ec7u qu\u1ea3 t\u1ed5ng th\u1ec3<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><b>K\u1ebft h\u1ee3p:<\/b><span style=\"font-weight: 400;\"> Vi sinh v\u1eadt kh\u00f3 tho\u00e1t \u0111\u01b0\u1ee3c b\u1ea5t k\u1ef3 l\u1edbp n\u00e0o<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><b>So s\u00e1nh v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c tr\u00ean th\u1ecb tr\u01b0\u1eddng:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>STERIS Spor-Klenz:<\/b><span style=\"font-weight: 400;\"> Ch\u1ee9a PAA + H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> nh\u01b0ng n\u1ed3ng \u0111\u1ed9 PAA cao h\u01a1n (7-8%), ph\u00f9 h\u1ee3p cho kh\u1eed khu\u1ea9n m\u1ea1nh m\u00e0 d\u1ec5 g\u00e2y k\u00edch \u1ee9ng h\u01a1n<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Veltek DECON-SPORE:<\/b><span style=\"font-weight: 400;\"> T\u01b0\u01a1ng t\u1ef1 QT SPORICIDE nh\u01b0ng gi\u00e1 th\u00e0nh cao h\u01a1n 1.5-2 l\u1ea7n<\/span><\/li>\n<\/ul>\n<h2><b>Chi\u1ebfn L\u01b0\u1ee3c Lu\u00e2n Phi\u00ean H\u00f3a Ch\u1ea5t T\u1ed1i \u01afu (4 Tu\u1ea7n) \u0110\u1ec3 Ki\u1ec3m So\u00e1t Bi\u1ebfn Th\u1ec3 Vi Sinh<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">\u0110\u1ec3 <\/span><b>ho\u00e0n to\u00e0n ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n bi\u1ebfn th\u1ec3 kh\u00e1ng<\/b><span style=\"font-weight: 400;\">, chi\u1ebfn l\u01b0\u1ee3c lu\u00e2n phi\u00ean ph\u1ea3i s\u1eed d\u1ee5ng <\/span><b>4 c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng kh\u00e1c nhau<\/b><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tu\u1ea7n 1: PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> (QT SPORICIDE)<\/b><span style=\"font-weight: 400;\"> \u2014 T\u1ea5n c\u00f4ng b\u1eb1ng <\/span><b>oxy h\u00f3a m\u1ea1nh<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tu\u1ea7n 2: QUAT (QT Quat ho\u1eb7c Contec ProClin)<\/b><span style=\"font-weight: 400;\"> \u2014 T\u1ea5n c\u00f4ng b\u1eb1ng <\/span><b>t\u01b0\u01a1ng t\u00e1c t\u0129nh \u0111i\u1ec7n<\/b><span style=\"font-weight: 400;\"> (ho\u00e0n to\u00e0n kh\u00e1c)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tu\u1ea7n 3: H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> 6% (QT PEROXY ho\u1eb7c Contec HydroKlean)<\/b><span style=\"font-weight: 400;\"> \u2014 Oxy h\u00f3a nh\u1eb9 h\u01a1n, ki\u1ec3m tra xem c\u00f3 vi sinh v\u1eadt n\u00e0o s\u1ed1ng s\u00f3t kh\u00f4ng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tu\u1ea7n 4: IPA 70%<\/b><span style=\"font-weight: 400;\"> \u2014 T\u1ea5n c\u00f4ng b\u1eb1ng <\/span><b>l\u00e0m x\u01a1 h\u00f3a protein<\/b><span style=\"font-weight: 400;\"> (c\u01a1 ch\u1ebf ho\u00e0n to\u00e0n kh\u00e1c)<\/span><\/li>\n<\/ul>\n<blockquote><p><b>K\u1ebft Qu\u1ea3:<\/b><\/p>\n<ul>\n<li><b>4 c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng kh\u00e1c nhau,<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><b>r\u1ea5t kh\u00f3 \u0111\u1ec3 vi sinh v\u1eadt ph\u00e1t tri\u1ec3n kh\u00e1ng v\u1edbi t\u1ea5t c\u1ea3<\/b><\/li>\n<li><b>T\u1ef7 l\u1ec7 xu\u1ea5t hi\u1ec7n bi\u1ebfn th\u1ec3 \u0111a kh\u00e1ng<\/b><span style=\"font-weight: 400;\"> gi\u1ea3m xu\u1ed1ng <\/span><b>&lt; 1%<\/b><span style=\"font-weight: 400;\"> (thay v\u00ec 30-50% khi ch\u1ec9 d\u00f9ng 1 h\u00f3a ch\u1ea5t)<\/span><\/li>\n<li><b>Vi sinh v\u1eadt kh\u00f4ng bao gi\u1edd &#8220;quen&#8221; \u0111\u01b0\u1ee3c<\/b><span style=\"font-weight: 400;\"> v\u1edbi b\u1ea5t k\u1ef3 m\u1ed9t h\u00f3a ch\u1ea5t n\u00e0o<\/span><\/li>\n<\/ul>\n<\/blockquote>\n<h2><b>Nh\u1eefng Th\u00e1ch Th\u1ee9c Khi S\u1eed D\u1ee5ng Peracetic Acid\u2014 R\u1ee7i Ro V\u00e0 Gi\u1ea3i Ph\u00e1p<\/b><\/h2>\n<figure id=\"attachment_9645\" aria-describedby=\"caption-attachment-9645\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"size-full wp-image-9645\" src=\"https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/4.png\" alt=\"nhung-thach-thuc-khi-su-dung-peracetic-acid\" width=\"600\" height=\"600\" srcset=\"https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/4.png 600w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/4-300x300.png 300w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/4-150x150.png 150w, https:\/\/sepro.vn\/wp-content\/uploads\/2026\/04\/4-100x100.png 100w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption id=\"caption-attachment-9645\" class=\"wp-caption-text\"><em>Nh\u1eefng th\u00e1ch th\u1ee9c khi s\u1eed d\u1ee5ng Peracetic Acid<\/em><\/figcaption><\/figure>\n<h3><b>1. \u0110\u1ed9c T\u00ednh Cao<\/b><\/h3>\n<p><b>N\u1ed3ng \u0111\u1ed9 kh\u00ed PAA:<\/b><span style=\"font-weight: 400;\"> Theo h\u01b0\u1edbng d\u1eabn c\u1ee7a <\/span><b>ACGIH (American Conference of Governmental Industrial Hygienists)<\/b><span style=\"font-weight: 400;\">, <\/span><b>TLV-STEL = 0.4 ppm<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>Nguy c\u01a1:<\/b><span style=\"font-weight: 400;\"> H\u00edt ph\u1ea3i PAA, <\/span><b>k\u00edch \u1ee9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, m\u1eaft, da<\/b><span style=\"font-weight: 400;\"> nghi\u00eam tr\u1ecdng. N\u1ed3ng \u0111\u1ed9 cao h\u01a1n 0.4 ppm trong kh\u00f4ng kh\u00ed c\u00f3 th\u1ec3 g\u00e2y <\/span><b>vi\u00eam ph\u1ebf qu\u1ea3n, kh\u00f3 th\u1edf<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>So s\u00e1nh:<\/b><span style=\"font-weight: 400;\"> PAA \u0111\u1ed9c t\u00ednh <\/span><b>cao h\u01a1n 10-50 l\u1ea7n<\/b><span style=\"font-weight: 400;\"> so v\u1edbi QUAT \u1edf c\u00f9ng n\u1ed3ng \u0111\u1ed9 (QUAT khuy\u1ebfn c\u00e1o kh\u00f4ng qu\u00e1 5 ppm).<\/span><\/p>\n<p><b>Gi\u1ea3i ph\u00e1p:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">D\u00f9ng <\/span><b>PPE \u0111\u1ea7y \u0111\u1ee7<\/b><span style=\"font-weight: 400;\"> (m\u1eb7t n\u1ea1 ph\u00f2ng \u0111\u1ed9c, k\u00ednh b\u1ea3o v\u1ec7, qu\u1ea7n \u00e1o ch\u1ed1ng h\u00f3a ch\u1ea5t)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Th\u00f4ng gi\u00f3 t\u1ed1t<\/b><span style=\"font-weight: 400;\"> khi s\u1eed d\u1ee5ng PAA (HVAC ph\u1ea3i ho\u1ea1t \u0111\u1ed9ng \u00edt 15 l\u1ea7n\/gi\u1edd)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Gi\u00e1m s\u00e1t n\u1ed3ng \u0111\u1ed9<\/b><span style=\"font-weight: 400;\"> trong kh\u00f4ng kh\u00ed \u0111\u1ecbnh k\u1ef3 b\u1eb1ng c\u00e1c thi\u1ebft b\u1ecb \u0111o \u0111\u1eb7c bi\u1ec7t<\/span><\/li>\n<\/ul>\n<h3><b>2. G\u00e2y \u0102n M\u00f2n V\u1eadt Li\u1ec7u<\/b><\/h3>\n<p><b>Th\u00e9p kh\u00f4ng g\u1ec9 (304, 316):<\/b><span style=\"font-weight: 400;\"> Ti\u1ebfp x\u00fac PAA k\u00e9o d\u00e0i (&gt; 30 ph\u00fat), <\/span><b>\u0103n m\u00f2n c\u1ee5c b\u1ed9 (pitting corrosion)<\/b><span style=\"font-weight: 400;\"> \u2014 nh\u1eefng v\u1ebft r\u1ed7 nh\u1ecf tr\u00ean b\u1ec1 m\u1eb7t.<\/span><\/p>\n<p><b>V\u1ea5n \u0111\u1ec1:<\/b><span style=\"font-weight: 400;\"> Nh\u1eefng v\u1ebft r\u1ed7 n\u00e0y ch\u00ednh l\u00e0 <\/span><b>n\u01a1i \u1ea9n n\u00e1u c\u1ee7a vi sinh v\u1eadt,<\/b><span style=\"font-weight: 400;\">\u00a0h\u00ecnh th\u00e0nh biofilm v\u00e0 kh\u00f3 kh\u1eed khu\u1ea9n l\u1ea7n sau.<\/span><\/p>\n<p><b>Gi\u1ea3i ph\u00e1p:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>H\u1ea1n ch\u1ebf contact time<\/b><span style=\"font-weight: 400;\"> \u1edf <\/span><b>10-15 ph\u00fat<\/b><span style=\"font-weight: 400;\"> (kh\u00f4ng \u0111\u1ec3 qu\u00e1 l\u00e2u)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>R\u1eeda ngay sau khi kh\u1eed tr\u00f9ng<\/b><span style=\"font-weight: 400;\"> b\u1eb1ng n\u01b0\u1edbc v\u00f4 tr\u00f9ng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>L\u1ef1a ch\u1ecdn v\u1eadt li\u1ec7u:<\/b><span style=\"font-weight: 400;\"> \u01afu ti\u00ean th\u00e9p 316L (c\u1ea3i ti\u1ebfn h\u01a1n) ho\u1eb7c titan n\u1ebfu s\u1eed d\u1ee5ng PAA th\u01b0\u1eddng xuy\u00ean<\/span><\/li>\n<\/ul>\n<h3><b>3. T\u01b0\u01a1ng Th\u00edch V\u1edbi C\u00e1c Thi\u1ebft B\u1ecb CIP<\/b><\/h3>\n<p><b>V\u1ea5n \u0111\u1ec1:<\/b><span style=\"font-weight: 400;\"> M\u1ed9t s\u1ed1 <\/span><b>c\u1ea3m bi\u1ebfn<\/b><span style=\"font-weight: 400;\">, <\/span><b>van \u0111i\u1ec1u khi\u1ec3n<\/b><span style=\"font-weight: 400;\">, <\/span><b>b\u1ed9 l\u1ecdc<\/b><span style=\"font-weight: 400;\"> kh\u00f4ng ch\u1ecbu \u0111\u01b0\u1ee3c PAA l\u00e2u d\u00e0i v\u00ec PAA oxy h\u00f3a c\u00e1c v\u1eadt li\u1ec7u nh\u1ef1a v\u00e0 cao su.<\/span><\/p>\n<p><b>Gi\u1ea3i ph\u00e1p:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ki\u1ec3m tra danh s\u00e1ch v\u1eadt li\u1ec7u t\u01b0\u01a1ng th\u00edch<\/b><span style=\"font-weight: 400;\"> tr\u01b0\u1edbc khi tri\u1ec3n khai PAA<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ch\u1ecdn thi\u1ebft b\u1ecb CIP \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf ri\u00eang<\/b><span style=\"font-weight: 400;\"> cho PAA (\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng v\u1eadt li\u1ec7u kh\u00e1ng oxy h\u00f3a)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>B\u1ea3o tr\u00ec \u0111\u1ecbnh k\u1ef3<\/b><span style=\"font-weight: 400;\"> v\u00e0 thay th\u1ebf c\u00e1c b\u1ed9 ph\u1eadn b\u1ecb \u0103n m\u00f2n<\/span><\/li>\n<\/ul>\n<h3><b>4. Chi Ph\u00ed Cao H\u01a1n<\/b><\/h3>\n<p><b>Gi\u00e1 PAA:<\/b><span style=\"font-weight: 400;\"> Cao h\u01a1n <\/span><b>2-3 l\u1ea7n<\/b><span style=\"font-weight: 400;\"> so v\u1edbi QUAT v\u00e0 ethanol. Th\u00eam v\u00e0o \u0111\u00f3 l\u00e0 chi ph\u00ed PPE, ki\u1ec3m so\u00e1t kh\u00f4ng kh\u00ed, b\u1ea3o tr\u00ec thi\u1ebft b\u1ecb.<\/span><\/p>\n<p><b>Gi\u1ea3i ph\u00e1p:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Lu\u00e2n phi\u00ean h\u1ee3p l\u00fd:<\/b><span style=\"font-weight: 400;\"> D\u00f9ng PAA <\/span><b>1-2 l\u1ea7n\/tu\u1ea7n<\/b><span style=\"font-weight: 400;\"> (kh\u00f4ng h\u00e0ng ng\u00e0y) \u0111\u1ec3 <\/span><b>c\u00e2n b\u1eb1ng chi ph\u00ed-l\u1ee3i \u00edch<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>T\u00ednh ROI (Return on Investment):<\/b><span style=\"font-weight: 400;\"> PAA gi\u00fap <\/span><b>gi\u1ea3m r\u1ee7i ro h\u1ecfng h\u00f3c s\u1ea3n ph\u1ea9m, t\u0103ng \u0111\u1ed9 an to\u00e0n,<\/b><span style=\"font-weight: 400;\">\u00a0chi ph\u00ed d\u00e0i h\u1ea1n c\u00f3 l\u1ee3i (ti\u1ebft ki\u1ec7m \u0111\u01b0\u1ee3c chi ph\u00ed h\u1ee7y s\u1ea3n ph\u1ea9m b\u1ecb \u00f4 nhi\u1ec5m)<\/span><\/li>\n<\/ul>\n<h2><b>C\u00e1ch Pha Ch\u1ebf, B\u1ea3o Qu\u1ea3n V\u00e0 X\u1eed L\u00fd PAA An To\u00e0n<\/b><\/h2>\n<h3><b>1. T\u1ef7 L\u1ec7 Pha Ch\u1ebf PAA<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Theo b\u00e0i vi\u1ebft <\/span><a href=\"https:\/\/sepro.vn\/sporicide-diet-bao-tu-la-gi-va-tai-sao-no-khong-the-thieu-trong-phong-sach-gmp\/\"><b>Sporicide di\u1ec7t b\u00e0o t\u1eed l\u00e0 g\u00ec<\/b><\/a><b>:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>N\u1ed3ng \u0111\u1ed9 s\u1eed d\u1ee5ng:<\/b> <b>0.2-0.35%<\/b><span style=\"font-weight: 400;\"> (pha lo\u00e3ng t\u1eeb dung d\u1ecbch g\u1ed1c)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>V\u00ed d\u1ee5 t\u00ednh to\u00e1n:<\/b><span style=\"font-weight: 400;\"> N\u1ebfu PAA g\u1ed1c l\u00e0 <\/span><b>5-6%<\/b><span style=\"font-weight: 400;\">, pha lo\u00e3ng v\u1edbi n\u01b0\u1edbc v\u00f4 tr\u00f9ng theo t\u1ef7 l\u1ec7 <\/span><b>1:15-20<\/b>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">C\u1ea7n 10 l\u00edt PAA 0.2%, pha 0.2 l\u00edt PAA 5% + 9.8 l\u00edt n\u01b0\u1edbc v\u00f4 tr\u00f9ng<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ki\u1ec3m tra:<\/b> <b>\u0110o n\u1ed3ng \u0111\u1ed9 b\u1eb1ng test kit<\/b><span style=\"font-weight: 400;\"> tr\u01b0\u1edbc m\u1ed7i l\u1ea7n s\u1eed d\u1ee5ng (r\u1ea5t quan tr\u1ecdng!)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>L\u01b0u \u00fd:<\/b><span style=\"font-weight: 400;\"> PAA gi\u1ea3m hi\u1ec7u l\u1ef1c theo th\u1eddi gian, <\/span><b>ch\u1ec9 chu\u1ea9n b\u1ecb l\u01b0\u1ee3ng c\u1ea7n d\u00f9ng<\/b><span style=\"font-weight: 400;\">, kh\u00f4ng chu\u1ea9n b\u1ecb tr\u01b0\u1edbc<\/span><\/li>\n<\/ul>\n<h3><b>2. B\u1ea3o Qu\u1ea3n PAA<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nhi\u1ec7t \u0111\u1ed9:<\/b> <b>0\u00b0C &#8211; 35\u00b0C<\/b><span style=\"font-weight: 400;\"> (t\u1ee7 l\u1ea1nh \u0111\u01b0\u1ee3c, nh\u01b0ng kh\u00f4ng c\u1ea7n \u0111\u00f4ng l\u1ea1nh)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u00c1nh s\u00e1ng:<\/b><span style=\"font-weight: 400;\"> B\u1ea3o qu\u1ea3n trong <\/span><b>b\u00ecnh\/can kh\u00f4ng trong su\u1ed1t<\/b><span style=\"font-weight: 400;\"> (tr\u00e1nh \u00e1nh s\u00e1ng v\u00ec \u00e1nh s\u00e1ng l\u00e0m PAA ph\u00e2n h\u1ee7y nhanh)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>H\u00f3a ch\u1ea5t:<\/b><span style=\"font-weight: 400;\"> Kh\u00f4ng \u0111\u1ec3 g\u1ea7n <\/span><b>acid m\u1ea1nh ho\u1eb7c base<\/b><span style=\"font-weight: 400;\"> (c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng v\u00e0 g\u00e2y nguy hi\u1ec3m)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Th\u1eddi h\u1ea1n:<\/b> <b>6-12 th\u00e1ng<\/b><span style=\"font-weight: 400;\"> (t\u00f9y th\u01b0\u01a1ng hi\u1ec7u v\u00e0 \u0111i\u1ec1u ki\u1ec7n b\u1ea3o qu\u1ea3n)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ki\u1ec3m tra:<\/b><span style=\"font-weight: 400;\"> N\u1ebfu PAA chuy\u1ec3n sang <\/span><b>m\u00e0u n\u00e2u\/\u0111en<\/b><span style=\"font-weight: 400;\">, <\/span><b>kh\u00f4ng d\u00f9ng<\/b><span style=\"font-weight: 400;\"> (\u0111\u00e3 ph\u00e2n h\u1ee7y)<\/span><\/li>\n<\/ul>\n<h3><b>3. X\u1eed L\u00fd D\u01b0 L\u01b0\u1ee3ng PAA<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>D\u00f9ng NAT (Sodium thiosulfate):<\/b><span style=\"font-weight: 400;\"> \u0110\u1ec3 neutralize PAA c\u00f2n l\u1ea1i tr\u01b0\u1edbc khi x\u1ea3 n\u01b0\u1edbc th\u1ea3i<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ph\u1ea3n \u1ee9ng h\u00f3a h\u1ecdc:<\/b><span style=\"font-weight: 400;\"> NAT + PAA, axit axetic (kh\u00f4ng \u0111\u1ed9c h\u1ea1i) + H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O + Na<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">SO<\/span><span style=\"font-weight: 400;\">\u2084<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>T\u1ef7 l\u1ec7:<\/b><span style=\"font-weight: 400;\"> C\u1ea7n ~2 l\u1ea7n th\u1ec3 t\u00edch NAT \u0111\u1ec3 neutralize ho\u00e0n to\u00e0n PAA<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>X\u00e1c nh\u1eadn:<\/b><span style=\"font-weight: 400;\"> D\u00f9ng <\/span><b>test strip<\/b><span style=\"font-weight: 400;\"> \u0111\u1ec3 ki\u1ec3m tra PAA \u0111\u00e3 neutralize h\u1ebft (test strip s\u1ebd kh\u00f4ng c\u00f2n m\u00e0u n\u1eefa)<\/span><\/li>\n<\/ul>\n<h2><b>Nh\u1eefng V\u1ea5n \u0110\u1ec1 Ch\u01b0a \u0110\u01b0\u1ee3c Gi\u1ea3i Quy\u1ebft \u2014 Lu\u1eadn \u0110i\u1ec3m C\u1ee7a Chuy\u00ean Gia<\/b><\/h2>\n<blockquote><p><b>Ghi ch\u00fa:<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<ol>\n<li><span style=\"font-weight: 400;\">Ph\u1ea7n n\u00e0y n\u00eau ra c\u00e1c \u00fd ki\u1ebfn t\u1eeb c\u00e1c nh\u00e0 chuy\u00ean m\u00f4n, nh\u1eefng v\u1ea5n \u0111\u1ec1 ch\u01b0a c\u00f3 s\u1ef1 th\u1ed1ng nh\u1ea5t trong ng\u00e0nh, v\u00e0 nh\u1eefng c\u00e2u h\u1ecfi c\u00f2n m\u1edf v\u1ec1 PAA.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">\u0110\u00e2y l\u00e0 nh\u1eefng quan \u0111i\u1ec3m d\u1ef1a tr\u00ean kinh nghi\u1ec7m th\u1ef1c ti\u1ec5n c\u00f3 th\u1ec3 \u0111\u00fang ho\u1eb7c sai, m\u1ee5c \u0111\u00edch ch\u1ec9 mang t\u00ednh tham kh\u1ea3o \u0111\u1ec3 nh\u00e0 m\u00e1y d\u01b0\u1ee3c c\u00e2n nh\u1eafc k\u1ef9 khi tri\u1ec3n khai.<\/span><\/li>\n<\/ol>\n<\/blockquote>\n<h3><b>V\u1ea5n \u0110\u1ec1 1: C\u1ea3m Bi\u1ebfn Gi\u00e1m S\u00e1t Tr\u1ef1c Tuy\u1ebfn (Online Monitoring) \u2014 C\u00f4ng Ngh\u1ec7 Ch\u01b0a Ph\u1ed5 Bi\u1ebfn<\/b><\/h3>\n<h4><b>Quan \u0110i\u1ec3m T\u1eeb C\u1ed9ng \u0110\u1ed3ng K\u1ef9 Thu\u1eadt H\u00f3a D\u01b0\u1ee3c:<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">Hi\u1ec7n nay, c\u00e1c nh\u00e0 m\u00e1y d\u01b0\u1ee3c Vi\u1ec7t Nam v\u1eabn ch\u1ee7 y\u1ebfu <\/span><b>ki\u1ec3m tra n\u1ed3ng \u0111\u1ed9 PAA th\u1ee7 c\u00f4ng<\/b><span style=\"font-weight: 400;\"> b\u1eb1ng test strip ho\u1eb7c titration (chu\u1ea9n \u0111\u1ed9), m\u1ea5t th\u1eddi gian v\u00e0 d\u1ec5 sai s\u00f3t. Tuy nhi\u00ean, nh\u1eefng <\/span><b>c\u1ea3m bi\u1ebfn \u0111i\u1ec7n h\u00f3a th\u00f4ng minh<\/b><span style=\"font-weight: 400;\"> \u0111\u1ec3 theo d\u00f5i n\u1ed3ng \u0111\u1ed9 PAA <\/span><b>tr\u1ef1c ti\u1ebfp trong CIP circuits<\/b><span style=\"font-weight: 400;\"> \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n \u1edf n\u01b0\u1edbc ngo\u00e0i nh\u01b0ng <\/span><b>ch\u01b0a tr\u1edf th\u00e0nh ti\u00eau chu\u1ea9n<\/b><span style=\"font-weight: 400;\"> t\u1ea1i Vi\u1ec7t Nam v\u00ec:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gi\u00e1 th\u00e0nh cao (200-500 tri\u1ec7u \u0111\u1ed3ng\/b\u1ed9)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Y\u00eau c\u1ea7u x\u00e1c th\u1ef1c (validation) ph\u1ee9c t\u1ea1p theo GMP<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u01b0\u01a1ng th\u00edch v\u1edbi h\u1ec7 th\u1ed1ng SCADA hi\u1ec7n t\u1ea1i ch\u01b0a r\u00f5<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">N\u1ebfu tri\u1ec3n khai, \u0111i\u1ec1u n\u00e0y s\u1ebd <\/span><b>gi\u1ea3m r\u1ee7i ro qu\u00e1 li\u1ec1u ho\u1eb7c li\u1ec1u th\u1ea5p PAA<\/b><span style=\"font-weight: 400;\"> v\u00e0 <\/span><b>t\u0103ng \u0111\u1ed9 ki\u1ec3m so\u00e1t quy tr\u00ecnh<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3><b>V\u1ea5n \u0110\u1ec1 2: S\u1eed D\u1ee5ng H\u00f3a H\u1ecdc Xanh \u2014 Oxy H\u00f3a N\u00e2ng Cao (AOP) K\u1ebft H\u1ee3p PAA<\/b><\/h3>\n<h4><b>Quan \u0110i\u1ec3m T\u1eeb C\u1ed9ng \u0110\u1ed3ng K\u1ef9 S\u01b0 X\u1eed L\u00fd N\u01b0\u1edbc Th\u1ea3i:<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">PAA k\u1ebft h\u1ee3p v\u1edbi <\/span><b>tia UV ho\u1eb7c Ozone<\/b><span style=\"font-weight: 400;\"> (g\u1ecdi l\u00e0 Advanced Oxidation Processes \u2014 AOP) c\u00f3 th\u1ec3 ph\u00e2n h\u1ee7y <\/span><b>d\u01b0 l\u01b0\u1ee3ng kh\u00e1ng sinh kh\u00f3 ph\u00e2n h\u1ee7y<\/b><span style=\"font-weight: 400;\"> trong n\u01b0\u1edbc th\u1ea3i d\u01b0\u1ee3c ph\u1ea9m hi\u1ec7u qu\u1ea3 h\u01a1n 99%. Tuy nhi\u00ean:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ch\u01b0a c\u00f3 <\/span><b>h\u01b0\u1edbng d\u1eabn GMP c\u1ee5 th\u1ec3<\/b><span style=\"font-weight: 400;\"> cho vi\u1ec7c tri\u1ec3n khai AOP t\u1ea1i c\u00e1c nh\u00e0 m\u00e1y d\u01b0\u1ee3c<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gi\u00e1 th\u00e0nh <\/span><b>cao g\u1ea5p 5-10 l\u1ea7n<\/b><span style=\"font-weight: 400;\"> so v\u1edbi x\u1eed l\u00fd th\u00f4ng th\u01b0\u1eddng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u1ea1i Vi\u1ec7t Nam, <\/span><b>ch\u1ec9 2-3 nh\u00e0 m\u00e1y<\/b><span style=\"font-weight: 400;\"> \u0111\u00e3 th\u1eed nghi\u1ec7m ph\u01b0\u01a1ng ph\u00e1p n\u00e0y<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u0110\u00e2y l\u00e0 <\/span><b>t\u01b0\u01a1ng lai c\u1ee7a x\u1eed l\u00fd n\u01b0\u1edbc th\u1ea3i d\u01b0\u1ee3c ph\u1ea9m<\/b><span style=\"font-weight: 400;\"> nh\u01b0ng c\u00f2n <\/span><b>l\u00e2u<\/b><span style=\"font-weight: 400;\"> m\u1edbi tr\u1edf th\u00e0nh ti\u00eau chu\u1ea9n.<\/span><\/p>\n<h3><b>V\u1ea5n \u0110\u1ec1 3: S\u1ea3n Xu\u1ea5t PAA T\u1ea1i Ch\u1ed7 (In-situ Generation) \u2014 C\u00f4ng Ngh\u1ec7 M\u1edbi Ch\u01b0a X\u00e1c Th\u1ef1c<\/b><\/h3>\n<h4><b>Quan \u0110i\u1ec3m T\u1eeb C\u1ed9ng \u0110\u1ed3ng K\u1ef9 S\u01b0 H\u00f3a D\u01b0\u1ee3c:<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">M\u1ed9t s\u1ed1 nh\u00e0 m\u00e1y t\u1ea1i ch\u00e2u \u00c2u \u0111\u00e3 \u00e1p d\u1ee5ng <\/span><b>s\u1ea3n xu\u1ea5t PAA tr\u1ef1c ti\u1ebfp<\/b><span style=\"font-weight: 400;\"> t\u1eeb axit axetic + H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> b\u1eb1ng c\u00e1c l\u00f2 ph\u1ea3n \u1ee9ng d\u00f2ng ch\u1ea3y (flow reactors) \u0111\u1ec3 <\/span><b>gi\u1ea3m r\u1ee7i ro v\u1eadn chuy\u1ec3n PAA \u0111\u1eadm \u0111\u1eb7c<\/b><span style=\"font-weight: 400;\">. \u01afu \u0111i\u1ec3m:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u1ea1o PAA t\u01b0\u01a1i 100% (kh\u00f4ng b\u1ecb ph\u00e2n h\u1ee7y)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gi\u1ea3m chi ph\u00ed b\u1ea3o qu\u1ea3n<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Nh\u01b0ng <\/span><b>th\u00e1ch th\u1ee9c l\u1edbn<\/b><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Y\u00eau c\u1ea7u <\/span><b>validation \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh<\/b><span style=\"font-weight: 400;\"> c\u1ee7a reactor theo GMP (m\u1ed7i batch kh\u00e1c nhau)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u1ea1i Vi\u1ec7t Nam, <\/span><b>ch\u01b0a c\u00f3 case study n\u00e0o c\u00f4ng khai<\/b><span style=\"font-weight: 400;\"> v\u1ec1 ph\u01b0\u01a1ng ph\u00e1p n\u00e0y<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">R\u1ee7i ro k\u1ef9 thu\u1eadt cao n\u1ebfu c\u00e2n b\u1eb1ng h\u00f3a h\u1ecdc b\u1ecb sai<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Do \u0111\u00f3, <\/span><b>h\u1ea7u h\u1ebft nh\u00e0 m\u00e1y \u1edf VN v\u1eabn mua PAA th\u00e0nh ph\u1ea9m<\/b><span style=\"font-weight: 400;\"> t\u1eeb nh\u00e0 cung c\u1ea5p.<\/span><\/p>\n<h3><b>V\u1ea5n \u0110\u1ec1 4: Tranh C\u00e3i V\u1ec1 Hi\u1ec7u Qu\u1ea3 PAA Fogging \u1ede Ph\u00f2ng S\u1ea1ch D\u01b0\u1ee3c Vi\u1ec7t Nam<\/b><\/h3>\n<h4><b>Quan \u0110i\u1ec3m T\u1eeb C\u1ed9ng \u0110\u1ed3ng Chuy\u00ean Gia Ph\u00f2ng S\u1ea1ch:<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">PAA fogging (phun s\u01b0\u01a1ng PAA) l\u00e0 m\u1ed9t c\u00f4ng ngh\u1ec7 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 kh\u1eed khu\u1ea9n <\/span><b>to\u00e0n b\u1ed9 kh\u00f4ng gian ph\u00f2ng s\u1ea1ch<\/b><span style=\"font-weight: 400;\"> m\u00e0 kh\u00f4ng c\u1ea7n phun th\u1ee7 c\u00f4ng t\u1eebng ch\u1ed7. Tuy nhi\u00ean:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hi\u1ec7u qu\u1ea3 <\/span><b>ph\u1ee5 thu\u1ed9c nhi\u1ec1u v\u00e0o HVAC<\/b><span style=\"font-weight: 400;\"> c\u1ee7a ph\u00f2ng s\u1ea1ch<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">N\u1ebfu \u00e1p l\u1ef1c\/d\u00f2ng kh\u00ed kh\u00f4ng c\u00e2n b\u1eb1ng, PAA c\u00f3 th\u1ec3 b\u1ecb <\/span><b>lo\u1ea1i b\u1ecf tr\u01b0\u1edbc khi ti\u1ebfp x\u00fac<\/b><span style=\"font-weight: 400;\"> v\u1edbi b\u1ec1 m\u1eb7t<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u01b0\u01a1ng t\u00e1c v\u1edbi <\/span><b>b\u1ee5i v\u00e0 h\u1ea1t l\u01a1 l\u1eedng<\/b><span style=\"font-weight: 400;\"> c\u00f3 th\u1ec3 <\/span><b>trung h\u00f2a PAA<\/b><span style=\"font-weight: 400;\"> tr\u01b0\u1edbc khi kh\u1eed tr\u00f9ng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">T\u1ea1i Vi\u1ec7t Nam, <\/span><b>h\u1ea7u h\u1ebft nh\u00e0 m\u00e1y v\u1eabn d\u00f9ng phun b\u1ec1 m\u1eb7t th\u1ee7 c\u00f4ng<\/b><span style=\"font-weight: 400;\"> thay v\u00ec fogging<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">So s\u00e1nh <\/span><b>H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> vapor<\/b><span style=\"font-weight: 400;\"> (\u0111\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i h\u01a1n, v\u00ed d\u1ee5 s\u1ea3n ph\u1ea9m TOMI SteraMist): H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> vapor c\u00f3 <\/span><b>chi ph\u00ed cao h\u01a1n 2-3 l\u1ea7n<\/b><span style=\"font-weight: 400;\"> nh\u01b0ng <\/span><b>hi\u1ec7u qu\u1ea3 \u1ed5n \u0111\u1ecbnh h\u01a1n<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">PAA fogging l\u00e0 <\/span><b>l\u1ef1a ch\u1ecdn ti\u1ebft ki\u1ec7m h\u01a1n<\/b><span style=\"font-weight: 400;\"> nh\u01b0ng <\/span><b>ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c th\u1ef1c chi ti\u1ebft<\/b><span style=\"font-weight: 400;\"> \u1edf \u0111i\u1ec1u ki\u1ec7n Vi\u1ec7t Nam.<\/span><\/p>\n<h3><b>V\u1ea5n \u0110\u1ec1 5: S\u1eafc N\u1ed9i Soi V\u1edbi PAA \u2014 Hi\u1ec7u Qu\u1ea3 v\u00e0 \u0110\u1ed9 B\u1ec1n Thi\u1ebft B\u1ecb<\/b><\/h3>\n<h4><b>Quan \u0110i\u1ec3m T\u1eeb C\u1ed9ng \u0110\u1ed3ng Chuy\u00ean Gia Y T\u1ebf V\u00e0 di\u1ec7t khu\u1ea9n:<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">Theo Spaulding&#8217;s classification, c\u00e1c d\u1ee5ng c\u1ee5 n\u1ed9i soi h\u00f4 h\u1ea5p\/\u1ed5 b\u1ee5ng <\/span><b>b\u1eaft bu\u1ed9c di\u1ec7t khu\u1ea9n<\/b><span style=\"font-weight: 400;\">, nh\u01b0ng h\u1ea7u h\u1ebft <\/span><b>kh\u00f4ng ch\u1ecbu nhi\u1ec7t<\/b><span style=\"font-weight: 400;\"> (&gt; 60\u00b0C l\u00e0m h\u1ecfng quang h\u1ecdc). PAA l\u00e0 <\/span><b>gi\u1ea3i ph\u00e1p thay th\u1ebf t\u1ed1t<\/b><span style=\"font-weight: 400;\"> nh\u01b0ng:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ti\u1ebfp x\u00fac PAA <\/span><b>li\u00ean t\u1ee5c k\u00e9o d\u00e0i,<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><b>\u0103n m\u00f2n c\u00e1c chi ti\u1ebft kim lo\u1ea1i<\/b><span style=\"font-weight: 400;\"> tr\u00ean n\u1ed9i soi<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sau 100-200 l\u1ea7n di\u1ec7t khu\u1ea9n b\u1eb1ng PAA, <\/span><b>quang h\u1ecdc c\u00f3 th\u1ec3 b\u1ecb m\u1edd\/\u0111\u1ed9 s\u1eafc n\u00e9t gi\u1ea3m<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chi ph\u00ed <\/span><b>s\u1eeda ch\u1eefa n\u1ed9i soi cao<\/b><span style=\"font-weight: 400;\"> (20-50 tri\u1ec7u\/l\u1ea7n) &gt; chi ph\u00ed s\u1eed d\u1ee5ng h\u00f3a ch\u1ea5t<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">So v\u1edbi c\u00e1c h\u1ec7 th\u1ed1ng kh\u00e1c nh\u01b0 <\/span><b>STERIS System 1<\/b><span style=\"font-weight: 400;\"> (d\u00f9ng PAA nh\u01b0ng v\u1edbi b\u1ea3o v\u1ec7 thi\u1ebft b\u1ecb t\u1ed1t h\u01a1n): M\u1ed9t s\u1ed1 nh\u00e0 m\u00e1y <\/span><b>s\u1eed d\u1ee5ng PAA t\u1ed1i \u0111a 50 l\u1ea7n\/n\u0103m<\/b><span style=\"font-weight: 400;\"> \u0111\u1ec3 <\/span><b>c\u00e2n b\u1eb1ng an to\u00e0n s\u1ea3n ph\u1ea9m + \u0111\u1ed9 b\u1ec1n thi\u1ebft b\u1ecb<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<blockquote><p><b>Ghi Ch\u00fa Cu\u1ed1i:<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">C\u00e1c quan \u0111i\u1ec3m tr\u00ean \u0111\u1ea1i di\u1ec7n cho nh\u1eefng lu\u1eadn \u0111i\u1ec3m t\u1eeb c\u00e1c chuy\u00ean gia v\u00e0 c\u1ed9ng \u0111\u1ed3ng ng\u00e0nh, <\/span><b>ch\u01b0a c\u00f3 s\u1ef1 th\u1ed1ng nh\u1ea5t<\/b><span style=\"font-weight: 400;\">, v\u00e0 <\/span><b>c\u00f3 th\u1ec3 thay \u0111\u1ed5i<\/b><span style=\"font-weight: 400;\"> khi c\u00f3 th\u00eam d\u1eef li\u1ec7u khoa h\u1ecdc.\u00a0<\/span><\/li>\n<li><b>B\u1ea1n n\u00ean tham kh\u1ea3o h\u01b0\u1edbng d\u1eabn ch\u00ednh th\u1ee9c t\u1eeb B\u1ed9 Y T\u1ebf, FDA, EMA ho\u1eb7c tham v\u1ea5n nh\u00e0 cung c\u1ea5p h\u00f3a ch\u1ea5t<\/b><span style=\"font-weight: 400;\"> tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh tri\u1ec3n khai.<\/span><\/li>\n<\/ul>\n<\/blockquote>\n<h2><b>FAQ Nh\u1eefng C\u00e2u H\u1ecfi Th\u01b0\u1eddng G\u1eb7p V\u1ec1 Peracetic Acid<\/b><\/h2>\n<blockquote>\n<h3><b>Peracetic Acid C\u00f3 An To\u00e0n Kh\u00f4ng?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">An to\u00e0n n\u1ebfu tu\u00e2n th\u1ee7 SOP (quy tr\u00ecnh ho\u1ea1t \u0111\u1ed9ng ti\u00eau chu\u1ea9n) nh\u01b0ng \u0111\u1ed9c t\u00ednh cao h\u01a1n QUAT: N\u1ed3ng \u0111\u1ed9 kh\u00ed 0.4 ppm (ACGIH STEL) d\u1ec5 g\u00e2y k\u00edch \u1ee9ng. D\u00f9ng PPE \u0111\u1ea7y \u0111\u1ee7, th\u00f4ng gi\u00f3 t\u1ed1t, h\u1ea1n ch\u1ebf contact time \u1edf 10-15 ph\u00fat.<\/span><\/p>\n<h3><b>PAA C\u00f3 G\u00e2y \u0102n M\u00f2n Thi\u1ebft B\u1ecb Kh\u00f4ng?<\/b><\/h3>\n<p><b>C\u00f3 th\u1ec3<\/b><span style=\"font-weight: 400;\">, \u0111\u1eb7c bi\u1ec7t tr\u00ean th\u00e9p kh\u00f4ng g\u1ec9 304 n\u1ebfu ti\u1ebfp x\u00fac <\/span><b>qu\u00e1 30 ph\u00fat<\/b><span style=\"font-weight: 400;\">. Gi\u1ea3i ph\u00e1p: <\/span><b>H\u1ea1n ch\u1ebf contact time, r\u1eeda ngay sau kh\u1eed tr\u00f9ng, \u01b0u ti\u00ean th\u00e9p 316L<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3><b>T\u1ea1i Sao Ph\u1ea3i D\u00f9ng PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> Ch\u1ee9 Kh\u00f4ng Ph\u1ea3i PAA \u0110\u01a1n L\u1ebb?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u0110\u1ec3 ki\u1ec3m so\u00e1t bi\u1ebfn th\u1ec3 vi sinh v\u00e0 kh\u00e1ng ch\u00e9o. PAA + H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> t\u1ea5n c\u00f4ng vi sinh v\u1eadt b\u1eb1ng 2 c\u01a1 ch\u1ebf kh\u00e1c nhau c\u00f9ng l\u00fac, gi\u1ea3m t\u1ef7 l\u1ec7 xu\u1ea5t hi\u1ec7n bi\u1ebfn th\u1ec3 kh\u00e1ng t\u1eeb 30-50% xu\u1ed1ng 1-5%.<\/span><\/p>\n<h3><b>C\u00e1ch Mua PAA \u1ede Vi\u1ec7t Nam<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Xem th\u00eam t\u1ea1i <\/span><strong><a href=\"https:\/\/sepro.vn\/hoa-chat-khu-trung-quantumtec-giai-phap-toan-dien-cho-moi-truong-kiem-soat-nghiem-ngat\/\">H\u00d3A CH\u1ea4T KH\u1eec TR\u00d9NG QUANTUMTEC<\/a><\/strong><span style=\"font-weight: 400;\"> \u0111\u1ec3 t\u00ecm <\/span><b>nh\u00e0 cung c\u1ea5p peracetic acid uy t\u00edn<\/b><span style=\"font-weight: 400;\">. C\u00e1c nh\u00e0 cung c\u1ea5p ch\u00ednh \u1edf Vi\u1ec7t Nam g\u1ed3m:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>SEPRO Solutions:<\/b><span style=\"font-weight: 400;\"> Cung c\u1ea5p QT SPORICIDE, QT Quat, QT PEROXY<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ecolab:<\/b><span style=\"font-weight: 400;\"> Cung c\u1ea5p c\u00e1c h\u00f3a ch\u1ea5t Quaternary, H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>STERIS:<\/b><span style=\"font-weight: 400;\"> Cung c\u1ea5p Spor-Klenz, System 1 disinfectant<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Contec:<\/b><span style=\"font-weight: 400;\"> Cung c\u1ea5p ProClin, PeridoxRTU, HydroKlean<\/span><\/li>\n<\/ul>\n<h3><b>L\u00e0m Sao Bi\u1ebft PAA \u0110\u00e3 H\u1ebft Hi\u1ec7u L\u1ef1c?<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>M\u00e0u s\u1eafc:<\/b><span style=\"font-weight: 400;\"> Chuy\u1ec3n sang <\/span><b>n\u00e2u\/\u0111en<\/b><span style=\"font-weight: 400;\"> = kh\u00f4ng d\u00f9ng<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Test kit:<\/b><span style=\"font-weight: 400;\"> N\u1ed3ng \u0111\u1ed9 <\/span><b>&lt; 0.1%<\/b><span style=\"font-weight: 400;\"> = kh\u00f4ng hi\u1ec7u qu\u1ea3<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>M\u00f9i:<\/b><span style=\"font-weight: 400;\"> M\u00f9i axetic <\/span><b>t\u1eaft \u0111i ho\u00e0n to\u00e0n<\/b><span style=\"font-weight: 400;\"> = h\u1ebft<\/span><\/li>\n<\/ul>\n<h3><b>PAA Kh\u00e1c V\u1edbi H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> \u1ede \u0110i\u1ec3m N\u00e0o?<\/b><\/h3>\n<ul>\n<li><b>PAA:<\/b><span style=\"font-weight: 400;\"> M\u1ea1nh h\u01a1n, hi\u1ec7u qu\u1ea3 tr\u00ean b\u00e0o t\u1eed, \u0111\u1ed9c t\u00ednh cao, k\u1ebft h\u1ee3p t\u1ed1t v\u1edbi H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><\/li>\n<li><b>H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b>:<\/b><span style=\"font-weight: 400;\"> An to\u00e0n h\u01a1n, hi\u1ec7u qu\u1ea3 th\u1ea5p khi d\u00f9ng \u0111\u01a1n l\u1ebb, ph\u00e2n h\u1ee7y th\u00e0nh n\u01b0\u1edbc + oxy<\/span><\/li>\n<\/ul>\n<\/blockquote>\n<h2><b>K\u1ebft Lu\u1eadn<\/b><\/h2>\n<p>Peracetic acid (PAA) l\u00e0 ch\u1ea5t oxy h\u00f3a m\u1ea1nh nh\u1ea5t trong arsenal c\u1ee7a nh\u00e0 m\u00e1y d\u01b0\u1ee3c hi\u1ec7n \u0111\u1ea1i, v\u1edbi kh\u1ea3 n\u0103ng ti\u00eau di\u1ec7t c\u1ea3 vi khu\u1ea9n l\u1eabn b\u00e0o t\u1eed trong 10-30 ph\u00fat. Tuy nhi\u00ean, \u0111\u1ed9c t\u00ednh cao, g\u00e2y \u0103n m\u00f2n v\u1eadt li\u1ec7u, chi ph\u00ed cao l\u00e0m cho PAA kh\u00f4ng ph\u1ea3i l\u1ef1a ch\u1ecdn cho to\u00e0n b\u1ed9 ch\u01b0\u01a1ng tr\u00ecnh kh\u1eed tr\u00f9ng.<\/p>\n<p><b>Chi\u1ebfn l\u01b0\u1ee3c t\u1ed1i \u01b0u:<\/b><span style=\"font-weight: 400;\"> D\u00f9ng <\/span><b>PAA + H<\/b><b>\u2082<\/b><b>O<\/b><b>\u2082<\/b><b> k\u1ebft h\u1ee3p<\/b><span style=\"font-weight: 400;\"> (nh\u01b0 QT SPORICIDE) <\/span><b>1-2 l\u1ea7n\/tu\u1ea7n<\/b><span style=\"font-weight: 400;\"> trong <\/span><b>lu\u00e2n phi\u00ean h\u00f3a ch\u1ea5t<\/b><span style=\"font-weight: 400;\"> (PAA+H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> \u2192 QUAT \u2192 H<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\">O<\/span><span style=\"font-weight: 400;\">\u2082<\/span><span style=\"font-weight: 400;\"> \u2192 IPA) \u0111\u1ec3:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>T\u1ed1i \u0111a h\u00f3a hi\u1ec7u qu\u1ea3 kh\u1eed tr\u00f9ng<\/b><span style=\"font-weight: 400;\"> v\u00e0 di\u1ec7t b\u00e0o t\u1eed<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ki\u1ec3m so\u00e1t bi\u1ebfn th\u1ec3 vi sinh<\/b><span style=\"font-weight: 400;\"> (gi\u1ea3m r\u1ee7i ro kh\u00e1ng ch\u00e9o t\u1eeb 30-50% xu\u1ed1ng &lt; 5%)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>C\u00e2n b\u1eb1ng chi ph\u00ed v\u00e0 an to\u00e0n nh\u00e2n vi\u00ean<\/b><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Trong ng\u00e0nh d\u01b0\u1ee3c ph\u1ea9m, peracetic acid (PAA \u2014 axit peracetic) l\u00e0 m\u1ed9t trong nh\u1eefng t\u00e1c nh\u00e2n oxy h\u00f3a m\u1ea1nh nh\u1ea5t \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 di\u1ec7t khu\u1ea9n b\u1ec1 m\u1eb7t, thi\u1ebft b\u1ecb v\u00e0 m\u00f4i tr\u01b0\u1eddng ph\u00f2ng s\u1ea1ch. Tuy nhi\u00ean, b\u1ea1n c\u00f3 bi\u1ebft r\u1eb1ng PAA ho\u1ea1t \u0111\u1ed9ng ho\u00e0n to\u00e0n kh\u00e1c v\u1edbi QUAT v\u00e0 ethanol, c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng &hellip; <a href=\"https:\/\/sepro.vn\/vi\/peracetic-acid-paa-la-gi\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Peracetic Acid (PAA) L\u00e0 G\u00ec \u2014 \u1ee8ng D\u1ee5ng, C\u01a1 Ch\u1ebf T\u00e1c \u0110\u1ed9ng V\u00e0 Vai Tr\u00f2 Trong Kh\u1eed Tr\u00f9ng Ph\u00f2ng S\u1ea1ch GMP<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":9653,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[126],"tags":[],"class_list":["post-9640","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"_links":{"self":[{"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/posts\/9640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/comments?post=9640"}],"version-history":[{"count":6,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/posts\/9640\/revisions"}],"predecessor-version":[{"id":9656,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/posts\/9640\/revisions\/9656"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/media\/9653"}],"wp:attachment":[{"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/media?parent=9640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/categories?post=9640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sepro.vn\/vi\/wp-json\/wp\/v2\/tags?post=9640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}